node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG2918 | Hsc70-3 | FBpp0290016 | FBpp0073447 | EG:25E8.1 protein; It is involved in the biological process described with: multicellular organism reproduction; cellular response to hypoxia; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity). | 0.998 |
CG2918 | Sec61alpha | FBpp0290016 | FBpp0311774 | EG:25E8.1 protein; It is involved in the biological process described with: multicellular organism reproduction; cellular response to hypoxia; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. | Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. | 0.798 |
CG2918 | Sil1 | FBpp0290016 | FBpp0084244 | EG:25E8.1 protein; It is involved in the biological process described with: multicellular organism reproduction; cellular response to hypoxia; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. | Nucleotide exchange factor Sil1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity). Belongs to the SIL1 family. | 0.995 |
Hsc70-3 | CG2918 | FBpp0073447 | FBpp0290016 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity). | EG:25E8.1 protein; It is involved in the biological process described with: multicellular organism reproduction; cellular response to hypoxia; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. | 0.998 |
Hsc70-3 | Sec61alpha | FBpp0073447 | FBpp0311774 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity). | Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. | 0.886 |
Hsc70-3 | Sil1 | FBpp0073447 | FBpp0084244 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity). | Nucleotide exchange factor Sil1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity). Belongs to the SIL1 family. | 0.976 |
RpL23 | RpL35 | FBpp0071808 | FBpp0070767 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | 0.999 |
RpL23 | RpS15 | FBpp0071808 | FBpp0086269 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Ribosomal protein S15 (RpS15) encodes a protein that plays a role in assembly, structure and function of the ribosome and functions in protein synthesis. It is phosphorylated by the kinase encoded by Lrrk, causing protein synthesis upregulation; Belongs to the universal ribosomal protein uS19 family. | 0.999 |
RpL23 | RpS18 | FBpp0071808 | FBpp0085585 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA. | 0.999 |
RpL23 | Sec61alpha | FBpp0071808 | FBpp0311774 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. | 0.999 |
RpL23 | Sil1 | FBpp0071808 | FBpp0084244 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Nucleotide exchange factor Sil1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity). Belongs to the SIL1 family. | 0.960 |
RpL23 | mRpL12 | FBpp0071808 | FBpp0076238 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Mitochondrial ribosomal protein L12 (mRpL12) encodes a protein required for Cyclin D/Cdk4-driven cell growth. | 0.999 |
RpL23 | mRpL17 | FBpp0071808 | FBpp0302563 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Mitochondrial ribosomal protein L17, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. | 0.999 |
RpL23 | mRpS9 | FBpp0071808 | FBpp0081263 | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | Mitochondrial ribosomal protein S9; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. | 0.999 |
RpL35 | RpL23 | FBpp0070767 | FBpp0071808 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | 60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family. | 0.999 |
RpL35 | RpS15 | FBpp0070767 | FBpp0086269 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | Ribosomal protein S15 (RpS15) encodes a protein that plays a role in assembly, structure and function of the ribosome and functions in protein synthesis. It is phosphorylated by the kinase encoded by Lrrk, causing protein synthesis upregulation; Belongs to the universal ribosomal protein uS19 family. | 0.999 |
RpL35 | RpS18 | FBpp0070767 | FBpp0085585 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | Ribosomal protein S18 (RpS18) encodes a ribosomal protein located at the top of the head of the 40S subunit and contacts several helices of the 18S rRNA. | 0.999 |
RpL35 | Sec61alpha | FBpp0070767 | FBpp0311774 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | Sec61 alpha subunit (Sec61alpha) encodes a subunit of the the translocon, a protein-conducting channel that mediates the co-translational transport of nascent polypeptides into the endoplasmic reticulum. It is a subunit of the Sec61 heterotrimer that forms the core of translocon channel. | 0.999 |
RpL35 | Sil1 | FBpp0070767 | FBpp0084244 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | Nucleotide exchange factor Sil1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for an ER lumenal chaperone of HSP70 family (By similarity). Belongs to the SIL1 family. | 0.960 |
RpL35 | mRpL12 | FBpp0070767 | FBpp0076238 | Ribosomal protein L35, isoform A; mRNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); translation. | Mitochondrial ribosomal protein L12 (mRpL12) encodes a protein required for Cyclin D/Cdk4-driven cell growth. | 0.999 |