STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ms(3)K81Male sterile (3) K81; It is involved in the biological process described with: telomere capping (184 aa)    
Predicted Functional Partners:
CG9203
Maternal haploid; DNA binding. It is involved in the biological process described with: DNA repair
      
 0.860
Sdic1
Sperm-specific dynein intermediate chain 1, isoform A; Microtubule motor activity. It is involved in the biological process described with: microtubule-based movement
      
 0.699
yem
Yemanuclein; May play a key role in egg organization. May be a transcriptional regulator having a role in chromatin remodeling in concert with Hira, a histone chaperone. Involved in chromosome segregation by affecting kinetochores function in the first meiotic division
      
 0.550
CG4259
annotation not available
      
 0.540
HipHop
HP1-HOAP-interacting protein, isoform A; It is involved in the biological process described with: protection from non-homologous end joining at telomere; CENP-A containing nucleosome assembly; neurogenesis
    
 
0.513
cav
Telomere-binding protein cav; Caravaggio is a fast evolving gene that encodes HP1/ORC Associated Protein (HOAP). HOAP is a DNA binding protein strongly enriched at chromosome ends and required for telomere capping
      
 0.489
Rcd-1r
Rcd-1 related; It is involved in the biological process described with: spermatogenesis; reproductive process
      
 0.485
grp
Serine/threonine-protein kinase grp; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. May phosphorylate the CDC25 phosphatase stg, which promotes its degradation. This results in increased inhibitory tyrosine phosphorylation of Cdk1-cyclin complexes and consequent inhibition of cell cycle progression
    
   0.476
CG31010
annotation not available
   
  
 0.466
nsr
Novel spermatogenesis regulator, isoform A; RNA binding. It is involved in the biological process described with: sperm axoneme assembly; posttranscriptional regulation of gene expression; sperm individualization
   
  
 0.454
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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