node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10365 | CG2540 | FBpp0083838 | FBpp0073508 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.913 |
CG10365 | superdeath | FBpp0083838 | FBpp0084751 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Aminopeptidase; Zinc ion binding; peptide binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis. | 0.900 |
CG2540 | CG10365 | FBpp0073508 | FBpp0083838 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.913 |
CG2540 | superdeath | FBpp0073508 | FBpp0084751 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Aminopeptidase; Zinc ion binding; peptide binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis. | 0.900 |
CG5493 | Eip55E | FBpp0085892 | FBpp0311547 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | 0.964 |
CG5493 | Gclc | FBpp0085892 | FBpp0309124 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | 0.804 |
CG5493 | Gclm | FBpp0085892 | FBpp0306672 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | 0.816 |
CG5493 | Got1 | FBpp0085892 | FBpp0086370 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis. | 0.912 |
CG5493 | Got2 | FBpp0085892 | FBpp0077537 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Aspartate aminotransferase; Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. | 0.913 |
CG5493 | Kyat | FBpp0085892 | FBpp0081994 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Kynurenine aminotransferase, isoform A; Pyridoxal phosphate binding; cysteine-S-conjugate beta-lyase activity; kynurenine-oxoglutarate transaminase activity. It is involved in the biological process described with: biosynthetic process; kynurenine metabolic process. | 0.900 |
CG5493 | superdeath | FBpp0085892 | FBpp0084751 | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | Aminopeptidase; Zinc ion binding; peptide binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis. | 0.800 |
Eip55E | CG5493 | FBpp0311547 | FBpp0085892 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | 0.964 |
Eip55E | Gclc | FBpp0311547 | FBpp0309124 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | 0.895 |
Eip55E | Gclm | FBpp0311547 | FBpp0306672 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | 0.897 |
Eip55E | Got1 | FBpp0311547 | FBpp0086370 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Glutamate oxaloacetate transaminase 1 (Got1) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis. | 0.954 |
Eip55E | Got2 | FBpp0311547 | FBpp0077537 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Aspartate aminotransferase; Glutamate oxaloacetate transaminase 2 (Got2) encodes an L-aspartate:2-oxoglutarate aminotransferase involved in glutamate biosynthesis, which in turn regulates postsynaptic receptor field size. | 0.954 |
Eip55E | Kyat | FBpp0311547 | FBpp0081994 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Kynurenine aminotransferase, isoform A; Pyridoxal phosphate binding; cysteine-S-conjugate beta-lyase activity; kynurenine-oxoglutarate transaminase activity. It is involved in the biological process described with: biosynthetic process; kynurenine metabolic process. | 0.957 |
Eip55E | superdeath | FBpp0311547 | FBpp0084751 | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | Aminopeptidase; Zinc ion binding; peptide binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis. | 0.814 |
Gclc | CG5493 | FBpp0309124 | FBpp0085892 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | Cysteine dioxygenase activity; ferrous iron binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; L-cysteine catabolic process. | 0.804 |
Gclc | Eip55E | FBpp0309124 | FBpp0311547 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | Ecdysone-induced protein 55E (Eip55E) encodes a protein involved in glutathione biosynthesis. | 0.895 |