node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRWD3 | yem | FBpp0083988 | FBpp0303324 | BRWD3 (BRWD3) encodes a member of the Bromodomain and WD repeat_containing protein (BRWD) family. It regulates ecdysone and JAK-STAT signaling pathways and contributes to eye development, cell death and phagocytosis. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.677 |
CG14427 | CG9215 | FBpp0070970 | FBpp0073882 | RE73396p. | RH47711p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II. | 0.800 |
CG14427 | Cpr78Cb | FBpp0070970 | FBpp0305586 | RE73396p. | Cuticular protein 78Cb, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | 0.835 |
CG14427 | yem | FBpp0070970 | FBpp0303324 | RE73396p. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.606 |
CG14814 | yem | FBpp0070353 | FBpp0303324 | Uncharacterized protein, isoform B. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.750 |
CG9215 | CG14427 | FBpp0073882 | FBpp0070970 | RH47711p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II. | RE73396p. | 0.800 |
CG9215 | Cpr78Cb | FBpp0073882 | FBpp0305586 | RH47711p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II. | Cuticular protein 78Cb, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | 0.843 |
CG9215 | yem | FBpp0073882 | FBpp0303324 | RH47711p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.620 |
Cpr78Cb | CG14427 | FBpp0305586 | FBpp0070970 | Cuticular protein 78Cb, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | RE73396p. | 0.835 |
Cpr78Cb | CG9215 | FBpp0305586 | FBpp0073882 | Cuticular protein 78Cb, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | RH47711p; Zinc ion binding; DNA-binding transcription factor activity; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II. | 0.843 |
Cpr78Cb | yem | FBpp0305586 | FBpp0303324 | Cuticular protein 78Cb, isoform A; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.631 |
Daxx | asf1 | FBpp0078890 | FBpp0074715 | Daxx-like protein; Transcription regulator. Acts as a histone chaperone that facilitates deposition of histone H3.3. Has a role in chromatin remodeling together with asf1 and XNP. Has role in the transcriptional apoptotic response to oxidative and UV stress. | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | 0.735 |
Daxx | yem | FBpp0078890 | FBpp0303324 | Daxx-like protein; Transcription regulator. Acts as a histone chaperone that facilitates deposition of histone H3.3. Has a role in chromatin remodeling together with asf1 and XNP. Has role in the transcriptional apoptotic response to oxidative and UV stress. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.646 |
Hira | asf1 | FBpp0071028 | FBpp0074715 | Protein HIRA homolog; Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Required for replication-independent chromatin assembly. Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3.3 and histone H4. Belongs to the WD repeat HIR1 family. | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | 0.994 |
Hira | yem | FBpp0071028 | FBpp0303324 | Protein HIRA homolog; Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Required for replication-independent chromatin assembly. Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3.3 and histone H4. Belongs to the WD repeat HIR1 family. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.964 |
Upf1 | yem | FBpp0073433 | FBpp0303324 | Regulator of nonsense transcripts 1 homolog; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity). | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.542 |
asf1 | Daxx | FBpp0074715 | FBpp0078890 | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | Daxx-like protein; Transcription regulator. Acts as a histone chaperone that facilitates deposition of histone H3.3. Has a role in chromatin remodeling together with asf1 and XNP. Has role in the transcriptional apoptotic response to oxidative and UV stress. | 0.735 |
asf1 | Hira | FBpp0074715 | FBpp0071028 | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | Protein HIRA homolog; Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Required for replication-independent chromatin assembly. Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3.3 and histone H4. Belongs to the WD repeat HIR1 family. | 0.994 |
asf1 | yem | FBpp0074715 | FBpp0303324 | Histone chaperone asf1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Plays a role in the formation of silent heterochromatin. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.871 |
ms(3)K81 | yem | FBpp0084435 | FBpp0303324 | Male sterile (3) K81 (ms(3)K81) encodes a telomere capping protein that is required to protect sperm telomeres from end-to-end fusion at fertilization. The ms(3)K81 product replaces its paralog HipHop in post-meiotic male germ cell nuclei. | Yemanuclein (yem) is a maternally expressed gene essential in the oocyte for meiosis and in the zygote for male pronucleus chromatin assembly. yem encodes a chaperone of H3.3 histone variant in partnership with the protein encoded by Hira. It also interacts with components of the Cohesin and the synaptonemal complexes. | 0.668 |