STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG31524Uncharacterized protein, isoform A; L-ascorbic acid binding; procollagen-proline 4-dioxygenase activity; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. It is involved in the biological process described with: oxidation-reduction process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline. (536 aa)    
Predicted Functional Partners:
CG31680
Uncharacterized protein; It is involved in the biological process described with: multicellular organism reproduction.
   
    0.697
CG9997
Uncharacterized protein, isoform A; CG9997 encodes a protein with homology to serine-type endopeptidases, but is not predicted to have catalytic activity due to mutations in its active site. It is produced in the male accessory gland and transferred to females during mating. In males, it is required for other seminal proteins to be transferred to mated females. In mated females, it is required for the binding of the product of SP to sperm and for the maintenance of long-term post-mating responses.
   
   0.683
S-Lap4
Sperm-Leucylaminopeptidase 4; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
   
 
  0.670
S-Lap8
Sperm-Leucylaminopeptidase 8; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
   
 
  0.670
loopin-1
Loopin-1, isoform A; Loopin-1 (loopin-1) encodes a testis-specific protein with homology to several leucine aminopeptidases. Sequence analysis suggest that it doesn't have enzymatic activity. It accumulates inside the axoneme-associated mitochondrial derivative in mature sperms.
   
 
  0.670
S-Lap1
Sperm-Leucylaminopeptidase 1; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: mushroom body development; proteolysis.
   
 
  0.667
S-Lap2
Sperm-Leucylaminopeptidase 2; Aminopeptidase activity; metalloexopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis.
   
 
  0.667
S-Lap5
Sperm-Leucylaminopeptidase 5; Metalloexopeptidase activity; aminopeptidase activity; manganese ion binding. It is involved in the biological process described with: proteolysis; mesoderm development.
   
 
  0.666
slgA
Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.660
P5cr-2
Pyrroline-5-carboxylate reductase activity. It is involved in the biological process described with: oxidation-reduction process; L-proline biosynthetic process.
     
  0.650
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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