STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1607Uncharacterized protein, isoform C; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport. (507 aa)    
Predicted Functional Partners:
CD98hc
CD98 heavy chain (CD98hc) encodes a transporter involved in the transmembrane import of L-leucine.
   
 
 0.752
twit
Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.
      
 0.600
CG10962
FI06485p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.550
CG5535
Uncharacterized protein, isoform C; L-ornithine transmembrane transporter activity; amino acid transmembrane transporter activity; L-lysine transmembrane transporter activity; arginine transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport; L-ornithine transmembrane transport; amino acid transport; L-arginine import across plasma membrane.
  
 
0.510
Mal-A5
Maltase A5, isoform A; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process.
   
 
 0.502
CG44153
Uncharacterized protein, isoform A; G protein-coupled receptor activity; cell-cell adhesion mediator activity. It is involved in the biological process described with: axon guidance; dendrite self-avoidance; homophilic cell adhesion via plasma membrane adhesion molecules.
      
 0.493
Eaat2
Excitatory amino acid transporter 2 (Eaat2) encodes a transmembrane protein involved in aspartate and taurine transport.
  
  
 0.480
Eaat1
Excitatory amino acid transporter 1 (Eaat1) encodes a transmembrane protein with a glutamate:sodium symporter activity. It is regulated by Notch signalling and contributes to larval locomotion and lifespan.
  
  
 0.465
CG13384
Uncharacterized protein, isoform C; Amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.
   
  
 0.458
NELF-B
Negative elongation factor B; Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II.
      
 0.435
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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