node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arf79F | ArfGAP3 | FBpp0078224 | FBpp0304160 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | 0.893 |
Arf79F | Sec23 | FBpp0078224 | FBpp0301099 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.859 |
Arf79F | alphaCOP | FBpp0078224 | FBpp0072694 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. | 0.863 |
Arf79F | beta'COP | FBpp0078224 | FBpp0080048 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). | 0.878 |
Arf79F | betaCOP | FBpp0078224 | FBpp0074348 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. | 0.956 |
Arf79F | deltaCOP | FBpp0078224 | FBpp0070355 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | 0.898 |
Arf79F | epsilonCOP | FBpp0078224 | FBpp0078891 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. | 0.890 |
Arf79F | gammaCOP | FBpp0078224 | FBpp0303129 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. Involved in the expansion of luminal extracellular matrices and apical membrane during tubulogenesis. Required [...] | 0.958 |
Arf79F | garz | FBpp0078224 | FBpp0087010 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Gartenzwerg, isoform B; Gartenzwerg (garz) encodes a guanine nucleotide exchange factor localized to the cis-Golgi apparatus. The roles of the product of garz include membrane and protein trafficking between the Golgi apparatus and the endoplasmic reticulum. It is required for epithelial morphogenesis in the embryo. | 0.993 |
Arf79F | zetaCOP | FBpp0078224 | FBpp0075111 | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. | 0.872 |
ArfGAP3 | Arf79F | FBpp0304160 | FBpp0078224 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | ADP-ribosylation factor 1; GTP-binding protein involved in protein trafficking; has a role in Golgi organization and may modulate vesicle budding and uncoating within the Golgi apparatus (Probable). Has a role in eye development. Required for cleavage furrow ingression in embryonic cells. | 0.893 |
ArfGAP3 | Sec23 | FBpp0304160 | FBpp0301099 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.445 |
ArfGAP3 | alphaCOP | FBpp0304160 | FBpp0072694 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. | 0.947 |
ArfGAP3 | beta'COP | FBpp0304160 | FBpp0080048 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). | 0.980 |
ArfGAP3 | betaCOP | FBpp0304160 | FBpp0074348 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. | 0.979 |
ArfGAP3 | deltaCOP | FBpp0304160 | FBpp0070355 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. | 0.944 |
ArfGAP3 | epsilonCOP | FBpp0304160 | FBpp0078891 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. | 0.646 |
ArfGAP3 | gammaCOP | FBpp0304160 | FBpp0303129 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. Involved in the expansion of luminal extracellular matrices and apical membrane during tubulogenesis. Required [...] | 0.986 |
ArfGAP3 | garz | FBpp0304160 | FBpp0087010 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Gartenzwerg, isoform B; Gartenzwerg (garz) encodes a guanine nucleotide exchange factor localized to the cis-Golgi apparatus. The roles of the product of garz include membrane and protein trafficking between the Golgi apparatus and the endoplasmic reticulum. It is required for epithelial morphogenesis in the embryo. | 0.824 |
ArfGAP3 | zetaCOP | FBpp0304160 | FBpp0075111 | ADP-ribosylation factor GTPase activating protein 3 (ArfGAP3) a GTPase activating proteins for Arf family GTPases. Arf proteins regulate actin dynamics, cell shape, and cell positioning within epithelia such as the eye. | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. | 0.901 |