STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG31612IP01335p; Sequence-specific DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: positive regulation of nuclear cell cycle DNA replication; regulation of transcription by RNA polymerase II. (987 aa)    
Predicted Functional Partners:
CG15394
Uncharacterized protein, isoform C.
      
 0.838
GCS2beta
Glucosidase 2 beta subunit, isoform A; It is involved in the biological process described with: N-glycan processing.
   
 
 0.837
l(2)05287
Lethal (2) 05287.
      
 0.829
CG42329
NRF domain-containing protein; Transferase activity, transferring acyl groups other than amino-acyl groups.
      
 0.679
CG8677
Uncharacterized protein, isoform B; CG8677 encodes a protein that dimerizes with the product of Iswi to form a chromatin remodeling factor RSF (remodeling and spacing factor). RSF is involved in silent chromatin formation via replacement of the product of His2Av.
   
 
 0.678
CG31495
RE10813p; ATPase activity; ATP binding. It is involved in the biological process described with: intra-Golgi vesicle-mediated transport; Golgi vesicle docking; Golgi to plasma membrane protein transport; SNARE complex disassembly.
   
  
 0.674
dtr
Dynein assembly factor 1, axonemal homolog; Cilium-specific protein required for cilia structures. Belongs to the DNAAF1 family.
    
 
 0.669
CRAT
Carnitine O-acetyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; carnitine metabolic process, CoA-linked; Belongs to the carnitine/choline acetyltransferase family.
      
 0.669
sut1
Sugar transporter 1; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
    
 
 0.669
fd3F
Forkhead domain 3F (fd3F) encodes a trancription factor that contributes to the specialization of mechanosensory cilium.
    
 
 0.628
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.