STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10465RE57120p; It is involved in the biological process described with: protein homooligomerization. (301 aa)    
Predicted Functional Partners:
CG17841
BcDNA.GH12326.
      
 0.847
CG15309
Protein yippee-like CG15309; Belongs to the yippee family.
      
 0.845
CG8209
GM09977p; Nucleic acid binding.
    
 
 0.812
CG8892
UBX domain-containing protein 7.
    
 
 0.804
casp
Caspar, isoform A; Caspar (casp) encodes a protein that inhibits the immune deficiency pathway, but not the Toll pathway, by blocking cleavage and nuclear translocation of the product of Rel.
   
 
 0.793
Cul3
Cullin 3, isoform F; Ubiquitin protein ligase binding; molecular adaptor activity; ubiquitin-protein transferase activity; protein binding; Belongs to the cullin family.
    
 
 0.728
Pis
CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content (By similarity). The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). Required for the regeneration of the signaling molecule phosphatidylinositol 4,5- bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing [...]
      
 0.714
CG14182
MIP13743p; It is involved in the biological process described with: negative regulation of smoothened signaling pathway.
      
 0.680
Eig71Eh
GEO13315p1; It is involved in the biological process described with: defense response to bacterium; metamorphosis.
      
 0.670
Eig71Ef
Ecdysone-induced gene 71Ef; It is involved in the biological process described with: defense response to bacterium.
      
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.