node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arl8 | Lrrk | FBpp0308780 | FBpp0306703 | ADP-ribosylation factor-like protein 8; Required for normal functioning of the late endocytic pathway including lysosome motility and late endosome-lysosome fusion. Not required for the delivery of lysosomal membrane protein-containing vesicles to late endosomes. In larval motorneurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. Essential role in chromosome segregation. | Leucine-rich repeat kinase (Lrrk) encodes a large Ser/Thr kinase involved in mRNA translational control, cytoskeleton regulation, vesicle trafficking, autophagy, and immune response. | 0.750 |
Arl8 | Rab2 | FBpp0308780 | FBpp0085458 | ADP-ribosylation factor-like protein 8; Required for normal functioning of the late endocytic pathway including lysosome motility and late endosome-lysosome fusion. Not required for the delivery of lysosomal membrane protein-containing vesicles to late endosomes. In larval motorneurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. Essential role in chromosome segregation. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.748 |
Arl8 | Vps16A | FBpp0308780 | FBpp0081459 | ADP-ribosylation factor-like protein 8; Required for normal functioning of the late endocytic pathway including lysosome motility and late endosome-lysosome fusion. Not required for the delivery of lysosomal membrane protein-containing vesicles to late endosomes. In larval motorneurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. Essential role in chromosome segregation. | Vacuolar protein sorting 16A (Vps16A) encodes a subunit of a heterohexameric tethering complex known as homotypic fusion and protein sorting (HOPS). HOPS roles include promoting the fusion of late endosomes, autophagosomes, biosynthetic vesicles, and lysosomes, and the biogenesis of lysosome-related eye pigment granules. The product of Vps16A is also part of miniCORVET (class C core vacuole/endosome tethering), a tethering complex involved in endosome maturation in nephrocytes and blood cells. | 0.690 |
Arl8 | Vps39 | FBpp0308780 | FBpp0083022 | ADP-ribosylation factor-like protein 8; Required for normal functioning of the late endocytic pathway including lysosome motility and late endosome-lysosome fusion. Not required for the delivery of lysosomal membrane protein-containing vesicles to late endosomes. In larval motorneurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function. Essential role in chromosome segregation. | Vacuolar protein sorting 39 (Vps39) encodes a subunit of the homotypic fusion and vacuole protein sorting (HOPS) complex required for autophagosome maturation. | 0.777 |
CG9356 | GCC185 | FBpp0081525 | FBpp0112136 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | 0.409 |
CG9356 | GCC88 | FBpp0081525 | FBpp0081842 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | 0.443 |
CG9356 | Gmap | FBpp0081525 | FBpp0423149 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | Golgi microtubule-associated protein (Gmap) encodes a peripheral Golgi protein that is required for the efficient trafficking within the early secretory pathway, probably by recruiting Rab proteins and effector molecules. | 0.554 |
CG9356 | Grasp65 | FBpp0081525 | FBpp0074664 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | 0.999 |
CG9356 | ICA69 | FBpp0081525 | FBpp0077950 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | Islet cell autoantigen 69 kDa (ICA69) encodes a protein that belongs to the BAR (Bin-Amphiphysin-Rvs) family of proteins. It regulates ionotropic glutamate receptor clustering at the neuromuscular junctions and controls synapse morphogenesis through a pathway that involves Spectrin and the product of Rab2. | 0.412 |
CG9356 | Rab2 | FBpp0081525 | FBpp0085458 | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.941 |
GCC185 | CG9356 | FBpp0112136 | FBpp0081525 | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | 0.409 |
GCC185 | GCC88 | FBpp0112136 | FBpp0081842 | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | 0.961 |
GCC185 | Gmap | FBpp0112136 | FBpp0423149 | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | Golgi microtubule-associated protein (Gmap) encodes a peripheral Golgi protein that is required for the efficient trafficking within the early secretory pathway, probably by recruiting Rab proteins and effector molecules. | 0.847 |
GCC185 | Grasp65 | FBpp0112136 | FBpp0074664 | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | 0.841 |
GCC185 | Rab2 | FBpp0112136 | FBpp0085458 | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.871 |
GCC88 | CG9356 | FBpp0081842 | FBpp0081525 | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | GH05665p; It is involved in the biological process described with: Golgi organization; Golgi to plasma membrane protein transport. | 0.443 |
GCC88 | GCC185 | FBpp0081842 | FBpp0112136 | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | GRIP and coiled-coil domain containing 185 kDa; Identical protein binding; ADP-ribosylation factor binding; Rab GTPase binding. | 0.961 |
GCC88 | Gmap | FBpp0081842 | FBpp0423149 | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | Golgi microtubule-associated protein (Gmap) encodes a peripheral Golgi protein that is required for the efficient trafficking within the early secretory pathway, probably by recruiting Rab proteins and effector molecules. | 0.674 |
GCC88 | Grasp65 | FBpp0081842 | FBpp0074664 | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | Grasp65 (Grasp65) encodes a myristoylated Golgi protein that binds the product of GM130 and has been shown to mediate the Golgi bypass of transmembrane proteins. | 0.649 |
GCC88 | Rab2 | FBpp0081842 | FBpp0085458 | GRIP and coiled-coil domain containing 88 kDa; ADP-ribosylation factor binding; Rab GTPase binding. It is involved in the biological process described with: Golgi vesicle transport. | Rab2, isoform A; Rab2 (Rab2) encodes a protein that belongs to the Rab family of small Ras-like GTPases that regulate vesicle trafficking. Rab2 product contributes to the maturation and fusion of endosomes and autophagosomes with lysosomes. | 0.755 |