STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
qsmQuasimodo, isoform A; Quasimodo (qsm) encodes a light-responsive factor of the circadian clock. It controls the rhythmic firing of clock neurons via the K[+] channel and the Na[+] K[+] Cl[-] cotransporter encoded by Shaw and NKCC respectively. (414 aa)    
Predicted Functional Partners:
NKCC
Sodium:potassium:chloride symporter activity; potassium:chloride symporter activity; sodium ion transmembrane transporter activity; sodium:chloride symporter activity; amino acid transmembrane transporter activity.
   
 
 0.845
Ncc69
Sodium chloride cotransporter 69 (Ncc69) encodes a member of the SLC12 family of Na[+]/K[+]/2Cl[-] cotransporters (NKCC).
    
 
 0.710
CG13377
RE15974p.
   
    0.660
Nnf1a
RE42502p; Nnf1a (Nnf1a) encodes a component of the Mis12 complex, which is an essential constituent of the kinetochore.
   
  
 0.602
mt:ND4
NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
   
 
 0.556
Shawl
Shaw-like, isoform C; Delayed rectifier potassium channel activity; voltage-gated potassium channel activity; voltage-gated cation channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; potassium ion transport; protein homooligomerization.
      
 0.555
CG32066
GH09096p.
      
 0.491
CG5001
FI02090p; Chaperone binding; unfolded protein binding. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; chaperone cofactor-dependent protein refolding.
   
   0.483
phr6-4
(6-4)-photolyase, isoform A; (6-4)-photolyase (phr6-4) encodes an enzyme that repairs DNA damage induced by ultraviolet light. It uses blue light and cofactor FADH to reverse the pyrimidine(6-4)pyrimidone photoproduct.
      
 0.469
Cda4
Chitin deacetylase-like 4; Chitin binding. It is involved in the biological process described with: chitin metabolic process; carbohydrate metabolic process.
   
  
 0.468
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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