STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbrd-2Testis-specifically expressed bromodomain containing protein-2 (tbrd-2) encodes a protein required for male fertility. It interacts with the products of tbrd-1, tbrd-3 and testis-specific TAFs. (674 aa)    
Predicted Functional Partners:
tbrd-3
Testis-specifically expressed bromodomain containing protein-3 (tbrd-3) encodes a protein that interacts with the products of tbrd-1, tbrd-2 and testis-specific TAFs.
   
 
 0.932
tbrd-1
Testis-specifically expressed bromodomain containing protein-1 (tbrd-1) encodes a protein involved in gene activation that is required for male germ cell differentiation. It interacts with the products of tbrd-2, tbrd-3 and testis-specific TAFs.
   
 
0.844
sa
Spermatocyte arrest (sa) encodes a testis binding protein associated factor involved in control of the male meiotic cycle, gene expression regulation, and spermatid differentiation.
   
 
 0.830
CG9173
Uncharacterized protein.
   
  
 0.821
Taf7
Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
    
 
 0.773
CG42828
BPTI/Kunitz inhibitor domain-containing protein; Serine-type endopeptidase inhibitor activity.
   
 
 0.698
CG13946
Uncharacterized protein.
   
  
 0.685
CG17917
Uncharacterized protein.
    
 
 0.684
CG42827
CG42827-PC, CG42827-PD; Serine-type endopeptidase inhibitor activity.
   
  
 0.681
CG31750
Uncharacterized protein CG31750.
      
 0.679
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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