STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG11906RE39769p; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated. (634 aa)    
Predicted Functional Partners:
bon
Bonus, isoform C; Bonus (bon) encodes a nuclear receptor cofactor involved in axon guidance and chromatin organization.
   
 0.537
prg
Piragua, isoform A; Piragua (prg) encodes a transcription factor that interacts genetically with fwe. It is required for embryonic dorsal closure and head involution as well as thorax and eye imaginal development.
   
 
  0.531
CG2116
LP13385p; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: dendrite morphogenesis; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated.
   
 
  0.419
D19B
GH09076p; DNA binding; DNA-binding transcription factor activity; zinc ion binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
 
  0.418
CG8159
RT10616p; Zinc ion binding; DNA-binding transcription factor activity; DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
 
  0.418
ATbp
AT-rich binding protein; May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions. Binds to AT rich DNA.
   
 
  0.418
D19A
RE29310p; DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
 
  0.417
ranshi
Ranshi (ranshi) encodes a protein involved in oocyte differentiation.
   
 
  0.410
M1BP
Motif 1 Binding Protein (M1BP) encodes a transcription pausing factor. It regulates gene transcription via interaction with the Hox proteins encoded by abd-A and Ubx. It contributes to the development of ovarian follicle cells.
   
 
  0.406
CG10274
Uncharacterized protein; DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
   
 
  0.406
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.