STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GstE6Glutathione S transferase E6 (GstE6) encodes an enzyme involved in glutathione metabolic processes. (222 aa)    
Predicted Functional Partners:
GstE7
Glutathione S transferase E7 (GstE7) encodes a cytosolic enzyme that functions in detoxication. It has high catalytic activity with various isothiocyanates and the toxic environmental pollutants 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
  
0.999
GstE5
Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process.
  
0.998
GluProRS
Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
 0.875
GstE8
Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process.
  
 
0.842
GstE3
Glutathione S transferase E3 (GstE3) encodes an enzyme involved in glutathione metabolic processes.
  
 
0.815
GstE9
Putative glutathione S-transferase; Glutathione S transferase E9 (GstE9) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
  
 
0.811
GstT1
Glutathione S transferase T1 (GstT1) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
  
 
0.783
GstD1
Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification.
  
 
0.759
GstT2
Glutathione S transferase T2 (GstT2) encodes an enzyme involved in glutathione metabolic processes; Belongs to the GST superfamily.
  
 
0.758
GstD3
Inactive glutathione S-transferase D3; Has no glutathione S-transferase activity. Belongs to the GST superfamily. Delta family.
  
 
0.751
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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