Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BubR1 | Chd3 | FBpp0085368 | FBpp0074766 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | 0.673 |
| BubR1 | Sse | FBpp0085368 | FBpp0076831 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | LD08709p; Separase (Sse) encodes an endoprotease. Together with the product of thr, it forms a complex which cleaves a subunit of the cohesin complex during meiosis, thereby allowing separation of the sister chromatids. | 0.984 |
| BubR1 | dgt5 | FBpp0085368 | FBpp0087059 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Augmin complex subunit dgt5; As part of the augmin complex, plays a role in centrosome- independent generation of spindle microtubules. The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules. | 0.499 |
| BubR1 | dup | FBpp0085368 | FBpp0086519 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins. | 0.633 |
| BubR1 | glu | FBpp0085368 | FBpp0080489 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Structural maintenance of chromosomes protein; Gluon (glu) encodes a subunit of the multiprotein complex condensin that is required for chromosome condensation and sister chromatid segregation. It contributes to nervous system development and glucose metabolism. | 0.786 |
| BubR1 | mu2 | FBpp0085368 | FBpp0072735 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Mutator 2 (mu2) encodes an androgen receptor co-activator involved in double-strand break repair and regulation of chromatin organization. | 0.431 |
| BubR1 | pim | FBpp0085368 | FBpp0304499 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Pimples, isoform A; Pimples (pim) encodes the Drosophila Securin homolog. Securins bind to the endoprotease Separase. In some species including Drosophila, this binding appears to promote proper folding of Separase. In addition, securin binding inhibits separase endoprotease activity in all species via an inhibitory pseudosubstrate region. | 0.481 |
| BubR1 | sti | FBpp0085368 | FBpp0304889 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Non-specific serine/threonine protein kinase; Sticky (sti) encodes a member of the AGC family of kinases that functions to regulate both actin-myosin-mediated cytokinesis and epigenetic gene silencing. | 0.590 |
| BubR1 | thr | FBpp0085368 | FBpp0309246 | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | Protein three rows; Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required. Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis. | 0.684 |
| Chd3 | BubR1 | FBpp0074766 | FBpp0085368 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Bub1-related kinase (BubR1) encodes a motif-rich protein with a C-terminal serine-threonine kinase domain. During prometaphase and metaphase, it plays important roles in spindle assembly checkpoint signalling, stabilization of kinetochore-microtuble attachments and chromosome alignment. It is also essential to maintain sister-chromatid cohesion during meiotic progression and for normal maintenance of Synaptonemal Complex in females. | 0.673 |
| Chd3 | RhoGAP54D | FBpp0074766 | FBpp0086058 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | 0.417 |
| Chd3 | Sse | FBpp0074766 | FBpp0076831 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | LD08709p; Separase (Sse) encodes an endoprotease. Together with the product of thr, it forms a complex which cleaves a subunit of the cohesin complex during meiosis, thereby allowing separation of the sister chromatids. | 0.668 |
| Chd3 | dgt5 | FBpp0074766 | FBpp0087059 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Augmin complex subunit dgt5; As part of the augmin complex, plays a role in centrosome- independent generation of spindle microtubules. The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules. | 0.406 |
| Chd3 | mu2 | FBpp0074766 | FBpp0072735 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Mutator 2 (mu2) encodes an androgen receptor co-activator involved in double-strand break repair and regulation of chromatin organization. | 0.642 |
| Chd3 | sti | FBpp0074766 | FBpp0304889 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Non-specific serine/threonine protein kinase; Sticky (sti) encodes a member of the AGC family of kinases that functions to regulate both actin-myosin-mediated cytokinesis and epigenetic gene silencing. | 0.456 |
| Chd3 | thr | FBpp0074766 | FBpp0309246 | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | Protein three rows; Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required. Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis. | 0.654 |
| RhoGAP54D | Chd3 | FBpp0086058 | FBpp0074766 | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | Chromodomain-helicase-DNA-binding protein 3; Chd3 (Chd3) encodes a nuclear ATP-dependent nucleosome remodeler of the CHD family. It associates with active chromatin and utilizes the energy of ATP hydrolysis to move nucleosomes along DNA. | 0.417 |
| RhoGAP54D | dup | FBpp0086058 | FBpp0086519 | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | Double parked (dup) encodes an essential protein for the initiation of DNA replication due to its recruitment of the MCM helicase to replication origins. | 0.410 |
| RhoGAP54D | sti | FBpp0086058 | FBpp0304889 | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | Non-specific serine/threonine protein kinase; Sticky (sti) encodes a member of the AGC family of kinases that functions to regulate both actin-myosin-mediated cytokinesis and epigenetic gene silencing. | 0.542 |
| RhoGAP54D | thr | FBpp0086058 | FBpp0309246 | Rho GTPase activating protein at 54D, isoform A; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; imaginal disc-derived leg morphogenesis. | Protein three rows; Required specifically for chromosome disjunction during all mitoses; maternally provided protein is sufficient until mitosis 14 then zygotic protein is required. Involved in formation and/or maintenance of epithelial structures: bud extension during Malpighian tubule development, and foregut and hindgut morphogenesis. | 0.517 |
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