STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NiPp1Nuclear inhibitor of Protein phosphatase 1 (NiPp1) encodes a PP1 phosphatase inhibitor involved in axon guidance. (383 aa)    
Predicted Functional Partners:
flw
Serine/threonine-protein phosphatase beta isoform; Required for cell adhesion in non-muscle tissues and in maintenance of muscle attachment. Vital for larval development. Belongs to the PPP phosphatase family. PP-1 subfamily.
   
 
 0.883
Pp1-87B
Serine/threonine-protein phosphatase alpha-2 isoform; Is essential for the regulation of mitotic chromosomal segregation as well as regulation of chromatin condensation during interphase; Belongs to the PPP phosphatase family. PP-1 subfamily.
   
 
 0.875
Pp1alpha-96A
Serine/threonine-protein phosphatase alpha-1 isoform; Protein phosphatase 1alpha at 96A (Pp1alpha-96A) encodes a phosphatase involved in the regulation of Hedgehog and Wnt signaling pathways.
   
 
 0.868
Pp1-13C
Serine/threonine-protein phosphatase alpha-3 isoform; Protein phosphatase 1 at 13C (Pp1-13C) encodes a phosphatase involved in hedgehog signaling regulation and sperm competition.
   
 
 0.835
CG14232
LD35087p; fatty-acyl-CoA binding.
      
 0.766
sds22
GH07711p; It is involved in the biological process described with: negative regulation of cell population proliferation; establishment or maintenance of polarity of larval imaginal disc epithelium; establishment or maintenance of polarity of follicular epithelium.
   
 
 0.766
I-3
Inhibitor-3; Protein serine/threonine phosphatase inhibitor activity; ubiquitin protein ligase activity; protein phosphatase 1 binding. It is involved in the biological process described with: negative regulation of protein dephosphorylation; negative regulation of phosphoprotein phosphatase activity; ubiquitin-dependent protein catabolic process.
      
 0.725
PpD6
Protein serine/threonine phosphatase activity. It is involved in the biological process described with: protein dephosphorylation; Belongs to the PPP phosphatase family.
   
 
 0.696
Sf3b1
Splicing factor 3b subunit 1, isoform A; RNA binding; mRNA binding. It is involved in the biological process described with: spliceosomal complex assembly; mRNA splicing, via spliceosome.
   
 
 0.673
shop
Probable sulfite oxidase, mitochondrial; Molybdenum ion binding; sulfite oxidase activity; heme binding; molybdopterin cofactor binding. It is involved in the biological process described with: sulfur compound metabolic process; nitrate assimilation; oxidation-reduction process.
      
 0.662
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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