STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lap1Protein lap1; May have a role in assembling adherens junctions. (849 aa)    
Predicted Functional Partners:
Torsin
Torsin-like protein; Torsin (Torsin) encodes an AAA-ATPase that is implicated in the export of large ribonuclear protein particles through the nuclear membrane. It regulates dopamine levels; Belongs to the ClpA/ClpB family. Torsin subfamily.
    
 
 0.891
Cirl
Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
   
 
 0.648
CG5103
FI06132p; Transketolase activity; thiamine pyrophosphate binding.
    
 
 0.606
Fili
Fish-lips, isoform C; Fish-lips (Fili) encodes a leucine-rich repeat family transmembrane protein. It regulates autonomous and nonautonomous apoptosis caused by the dioxin receptor homolog encoded by ss.
  
   
 0.538
Stip1
Stress induced phosphoprotein 1; Hsp90 protein binding.
    
 
 0.530
CG8036
LP07963p; Transketolase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: regulation of chromatin silencing.
    
 
 0.526
CG18095
Uncharacterized protein, isoform B.
  
     0.522
Lrt
Leucine-rich tendon-specific protein (Lrt) encodes a transmembrane protein expressed specifically in tendon cells. It binds to the product of robo1 and is required for proper patterning of the muscles.
  
     0.496
CG5810
Uncharacterized protein.
  
     0.488
Gp150
Gp150, isoform D; Gp150 (Gp150) encodes a transmembrane glycoprotein that regulates Notch signaling and is involved in eye development.
  
     0.484
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.