STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp6a22Cytochrome P450 6a22; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (499 aa)    
Predicted Functional Partners:
CG31769
RH26533p.
   
  
 0.689
CG7737
Uncharacterized protein, isoform B; Polyamine oxidase activity; oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process.
      
 0.680
CG13510
MIP04282p; It is involved in the biological process described with: cold acclimation.
    
 
 0.621
CG42565
GEO12575p1.
    
 
 0.620
CG17724
Uncharacterized protein, isoform E; Structural constituent of nuclear pore.
   
 
 0.618
CG8034
Uncharacterized protein, isoform A; Monocarboxylic acid transmembrane transporter activity. It is involved in the biological process described with: monocarboxylic acid transport; transmembrane transport.
   
  
 0.605
olf413
MOXD1 homolog 2; Dopamine beta-monooxygenase activity; copper ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen. It is involved in the biological process described with: dopamine catabolic process; oxidation-reduction process; octopamine biosynthetic process; norepinephrine biosynthetic process.
      
 0.602
GXIVsPLA2
Group XIV secreted phospholipase A2; Calcium ion binding; phospholipase A2 activity. It is involved in the biological process described with: arachidonic acid secretion; phospholipid metabolic process; lipid catabolic process.
      
 0.601
spo
Spook (spo) encodes a cytochrome P450 involved in ecdysteroid biosynthesis in the embryo. spo mutants fail to undergo head involution, dorsal closure or to secrete cuticle.
  
 
 0.526
l(1)G0193
Lethal (1) G0193, isoform A.
   
   0.523
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.