STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGBE1,4-Alpha-Glucan Branching Enzyme (AGBE) encodes a protein that is inferred to be a hydrolase involved in glycogen synthesis and hypoxia, based on the function of its orthologs. It contributes to the determination of lifespan. (685 aa)    
Predicted Functional Partners:
GlyP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). Required for glycogen breakdown in skeletal muscle.
 
 0.999
GlyS
Glycogen synthase (GlyS) encodes a glycosyltransferase that catalyzes linkage of glucose monomers into glycogen. Regulation of the product of GlyS activity by glucose 6-phosphate and phosphorylation helps control cellular glycogen levels.
 
 0.999
CG9485
Uncharacterized protein, isoform B; 4-alpha-glucanotransferase activity; amylo-alpha-1,6-glucosidase activity. It is involved in the biological process described with: glycogen biosynthetic process; glycogen catabolic process.
  
 
 0.991
Pgm1
Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
  
  
 0.977
Amyrel
Amyrel (Amyrel) encodes an amylolytic activity protein that is expressed mainly in larval midgut.
  
 
 0.956
Amy-d
Amylase distal (Amy-d) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
  
 
 0.955
Amy-p
Alpha-amylase B; Amylase proximal (Amy-p) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
  
 
 0.955
ATPsynbeta
ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...]
 
  
 0.925
UGP
UTP--glucose-1-phosphate uridylyltransferase; UGP (UGP) encodes an enzyme involved in hyperoxia response.
   
  
 0.922
Gyg
Glycogenin, isoform E; Glycogenin glucosyltransferase activity. It is involved in the biological process described with: glycogen biosynthetic process.
   
 0.915
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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