STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG8888GH26015p; Estradiol 17-beta-dehydrogenase activity; testosterone dehydrogenase (NAD+) activity. (388 aa)    
Predicted Functional Partners:
CG5543
Gastrulation defective protein 1 homolog; It is involved in the biological process described with: regulation of histone H2B conserved C-terminal lysine ubiquitination; regulation of DNA double-strand break processing; Belongs to the WD repeat GAD-1 family.
      
 0.835
CG10657
LD40136p; Phosphatidylinositol bisphosphate binding.
   
 0.770
Cralbp
Cellular retinaldehyde binding protein; Phosphatidylinositol bisphosphate binding; retinal binding.
   
 0.760
CG5177
Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.722
CG6337
RE20049p; Cysteine-type endopeptidase activity. It is involved in the biological process described with: proteolysis involved in cellular protein catabolic process; Belongs to the peptidase C1 family.
   
  
 0.687
CG1246
RE02644p.
   
  
 0.679
CG3246
FI04421p; Lipid binding.
      
 0.674
CG8066
GEO08281p1; Cysteine-type endopeptidase inhibitor activity.
      
 0.674
CG14762
MIP14966p.
   
  
 0.673
PIG-Z
GPI mannosyltransferase 4; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly (By similarity).
      
 0.673
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.