STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lambdaTryTrypsin-lambda; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (272 aa)    
Predicted Functional Partners:
baz
Bazooka, isoform B; Bazooka (baz) encodes a scaffold protein that forms a complex with the products of par-6 and aPKC and with other cortical, cytoskeletal and regulatory proteins. It functions in cell polarization pathways in epithelial, neuronal and other cell types.
     
  0.900
zetaTry
zetaTrypsin (zetaTry) encodes a putative digestive enzyme with predicted serine-type endopeptidase activity. zetaTry is highly expressed and enriched in the midgut and hindgut; Belongs to the peptidase S1 family.
  
  
0.858
CG9673
RE37738p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
   
0.844
sphe
Spheroide (sphe) encodes a serine protein homologue, a serine protease with no catalytic activity.
  
   
0.827
CG10472
RE65433p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
   
0.821
CG17475
Uncharacterized protein, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.805
Mal-A3
Maltase A3; Maltose alpha-glucosidase activity. It is involved in the biological process described with: carbohydrate metabolic process; Belongs to the glycosyl hydrolase 13 family.
   
    0.790
CG15255
Metalloendopeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
 
 
    0.790
CG18585
Uncharacterized protein, isoform A; Zinc ion binding; metallocarboxypeptidase activity. It is involved in the biological process described with: proteolysis.
 
 
   0.783
iotaTry
Trypsin iota; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
   
0.774
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.