STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BBS4Bardet-Biedl syndrome 4 protein homolog; May be required for microtubule anchoring at the centrosome. Required for ciliogenesis (By similarity); Belongs to the BBS4 family. (486 aa)    
Predicted Functional Partners:
BBS1
Bardet-Biedl syndrome 1; Patched binding; smoothened binding. It is involved in the biological process described with: protein localization to cilium; non-motile cilium assembly; cilium assembly.
   
 0.999
BBS5
Bardet-Biedl syndrome 5; Phosphatidylinositol-3-phosphate binding. It is involved in the biological process described with: cilium assembly; intracellular transport.
  
 0.999
BBS9
Bardet-Biedl syndrome 9; It is involved in the biological process described with: cilium assembly.
   
 0.999
BBS8
Bardet-Biedl syndrome 8; It is involved in the biological process described with: cilium assembly; non-motile cilium assembly.
  
 0.989
BBIP1
BBSome interacting protein 1; It is involved in the biological process described with: cilium assembly; receptor localization to non-motile cilium.
    
 0.959
cep290
Centrosomal protein cep290; Essential for ciliogenesis in sensory neurons and germ cells. During neuron and spermatocyte ciliogenesis, plays a role in transition zone assembly where it is required for the formation of diverse connections between microtubules and between microtubules and the membrane.
   
 
 0.887
IFT20
Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium.
    
 
 0.843
nompB
No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits.
      
 0.799
IFT57
Intraflagellar transport protein 57 homolog; Required for the formation of cilia; Belongs to the IFT57 family.
   
 
 0.781
Oseg5
Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly.
   
 
 0.774
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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