node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10918 | CG9757 | FBpp0076914 | FBpp0306563 | Uncharacterized protein. | GEO07284p1. | 0.844 |
CG10918 | Prx2540-1 | FBpp0076914 | FBpp0087356 | Uncharacterized protein. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.605 |
CG15550 | CG6023 | FBpp0085113 | FBpp0310654 | Uncharacterized protein. | Uncharacterized protein, isoform C. | 0.834 |
CG15550 | Prx2540-1 | FBpp0085113 | FBpp0087356 | Uncharacterized protein. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.546 |
CG6023 | CG15550 | FBpp0310654 | FBpp0085113 | Uncharacterized protein, isoform C. | Uncharacterized protein. | 0.834 |
CG6023 | Prx2540-1 | FBpp0310654 | FBpp0087356 | Uncharacterized protein, isoform C. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.523 |
CG6762 | Prx2540-1 | FBpp0074266 | FBpp0087356 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.620 |
CG6762 | Prx5 | FBpp0074266 | FBpp0100079 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | Peroxiredoxin 5 (Prx5) encodes an atypical member of the family of thiol-specific peroxidases that forms intramolecular disulfide bonds during the catalytic cycle. Its roles include antioxidant function, maintenance of cellular redox state, modulation of the immune-related signaling and protection against apoptosis. | 0.831 |
CG9314 | Cat | FBpp0308626 | FBpp0074825 | CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. | Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. | 0.906 |
CG9314 | Prx2540-1 | FBpp0308626 | FBpp0087356 | CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.618 |
CG9314 | Prx5 | FBpp0308626 | FBpp0100079 | CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. | Peroxiredoxin 5 (Prx5) encodes an atypical member of the family of thiol-specific peroxidases that forms intramolecular disulfide bonds during the catalytic cycle. Its roles include antioxidant function, maintenance of cellular redox state, modulation of the immune-related signaling and protection against apoptosis. | 0.480 |
CG9314 | Sod2 | FBpp0308626 | FBpp0311603 | CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. | Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress. | 0.613 |
CG9757 | CG10918 | FBpp0306563 | FBpp0076914 | GEO07284p1. | Uncharacterized protein. | 0.844 |
CG9757 | Prx2540-1 | FBpp0306563 | FBpp0087356 | GEO07284p1. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.605 |
Cat | CG9314 | FBpp0074825 | FBpp0308626 | Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. | CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process. | 0.906 |
Cat | Prx2540-1 | FBpp0074825 | FBpp0087356 | Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.618 |
Cat | Prx5 | FBpp0074825 | FBpp0100079 | Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. | Peroxiredoxin 5 (Prx5) encodes an atypical member of the family of thiol-specific peroxidases that forms intramolecular disulfide bonds during the catalytic cycle. Its roles include antioxidant function, maintenance of cellular redox state, modulation of the immune-related signaling and protection against apoptosis. | 0.480 |
Cat | Sod2 | FBpp0074825 | FBpp0311603 | Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species. | Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress. | 0.660 |
Hsc70-5 | Prx2540-1 | FBpp0086694 | FBpp0087356 | Heat shock 70 kDa protein cognate 5. | Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: hydrogen peroxide catabolic process; oxidation-reduction process; cell redox homeostasis. | 0.523 |
Hsc70-5 | Sod2 | FBpp0086694 | FBpp0311603 | Heat shock 70 kDa protein cognate 5. | Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress. | 0.586 |