STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12896DI01187p; Peroxiredoxin activity; peroxidase activity. It is involved in the biological process described with: cell redox homeostasis; oxidation-reduction process; mesoderm development; response to oxidative stress. (220 aa)    
Predicted Functional Partners:
CG15550
Uncharacterized protein.
      
 0.660
CG6023
Uncharacterized protein, isoform C.
      
 0.627
CG6762
Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family.
   
 
 0.620
Cat
Catalase (Cat) encodes an enzyme that catalyzes the decomposition of hydrogen peroxide. It reduces the amount of oxidative damage to biomolecules and protects cells from the toxic effects of reactive oxygen species.
  
 
 0.618
CG9314
CG9314 protein; Catalase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; hydrogen peroxide catabolic process; response to hydrogen peroxide; oxidation-reduction process.
  
 
 0.618
CG10211
LD42267p; Peroxidase activity; heme binding. It is involved in the biological process described with: response to oxidative stress; oxidation-reduction process.
      
 0.616
CG3609
LD06553p; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process.
      
 0.606
CG12338
RE49860p; D-amino-acid oxidase activity; FAD binding. It is involved in the biological process described with: oxidation-reduction process; D-amino acid metabolic process.
      
 0.566
Sod2
Superoxide dismutase 2 (Mn) (Sod2) encodes an enzyme that detoxifies superoxide radicals in mitochondria. The loss of Sod2 generates endogenous oxidative stress that results in reduced activity of critical mitochondrial enzymes, hypersensitivity to oxidative stress and neonatal lethality. A muscle restricted p38Kinase-Mef2-Sod2 signaling module influences life span and stress.
  
  
 0.542
CG9674
Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process.
    
 
 0.540
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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