node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apt1 | CG1407 | FBpp0303935 | FBpp0308508 | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | 0.645 |
Apt1 | Hip14 | FBpp0303935 | FBpp0303194 | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | Palmitoyltransferase Hip14; Probable palmitoyltransferase which is required for photoreceptor synaptic transmission and for the correct expression and localization of palmitoylated protein Csp and synaptosomal-associated protein Snap25. Probably palmitoylates Csp. Probably also palmitoylates the dorsal-ventral patterning protein Sog and promotes its secretion and activity and the stabilization of the membrane-bound form. Required for synaptic vesicle exocytosis. | 0.551 |
Apt1 | Patsas | FBpp0303935 | FBpp0423165 | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | 0.688 |
Apt1 | Ppt1 | FBpp0303935 | FBpp0311872 | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | Palmitoyl-protein thioesterase 1 (Ppt1) encodes a lysosomal enzyme that removes palmitoyl groups from particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. | 0.706 |
Apt1 | Ppt2 | FBpp0303935 | FBpp0079801 | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | Palmitoyl-protein Thioesterase 2 (Ppt2) encodes a lysosomal enzyme that removes palmitoyl groups form particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. | 0.649 |
CG10336 | CG1407 | FBpp0271702 | FBpp0308508 | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | 0.538 |
CG10336 | Claspin | FBpp0271702 | FBpp0312156 | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | Claspin; Required for checkpoint signaling in response to DNA replication stress; either resulting from normal embryogenesis or induced by the DNA synthesis inhibitor hydroxyurea (HU). It is not required for the G2 arrest resulting from DNA double strand breaks induced by ionizing irradiation (IR). Necessary for the timely phosphorylation of Cdk1 at the mid-blastula transition. May have a minor role in maintaining genomic stability in mitotic cells. Belongs to the claspin family. | 0.920 |
CG10336 | Marcal1 | FBpp0271702 | FBpp0078631 | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Marcal1 (Marcal1) encodes an ATP-dependent DNA annealing helicase that recognizes single-stranded to double-stranded DNA transitions. It maintains genomic integrity through its roles in DNA repair, DNA replication, DNA recombination and gene expression; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. | 0.438 |
CG10336 | RPA3 | FBpp0271702 | FBpp0310183 | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.961 |
CG10336 | mus302 | FBpp0271702 | FBpp0075105 | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | RE72625p; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein ubiquitination; interstrand cross-link repair. | 0.558 |
CG1407 | Apt1 | FBpp0308508 | FBpp0303935 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Uncharacterized protein, isoform E; Carboxylic ester hydrolase activity; palmitoyl-(protein) hydrolase activity. It is involved in the biological process described with: protein depalmitoylation. | 0.645 |
CG1407 | CG10336 | FBpp0308508 | FBpp0271702 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Protein TIPIN homolog; Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress (By similarity). | 0.538 |
CG1407 | Claspin | FBpp0308508 | FBpp0312156 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Claspin; Required for checkpoint signaling in response to DNA replication stress; either resulting from normal embryogenesis or induced by the DNA synthesis inhibitor hydroxyurea (HU). It is not required for the G2 arrest resulting from DNA double strand breaks induced by ionizing irradiation (IR). Necessary for the timely phosphorylation of Cdk1 at the mid-blastula transition. May have a minor role in maintaining genomic stability in mitotic cells. Belongs to the claspin family. | 0.579 |
CG1407 | Hip14 | FBpp0308508 | FBpp0303194 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Palmitoyltransferase Hip14; Probable palmitoyltransferase which is required for photoreceptor synaptic transmission and for the correct expression and localization of palmitoylated protein Csp and synaptosomal-associated protein Snap25. Probably palmitoylates Csp. Probably also palmitoylates the dorsal-ventral patterning protein Sog and promotes its secretion and activity and the stabilization of the membrane-bound form. Required for synaptic vesicle exocytosis. | 0.580 |
CG1407 | Marcal1 | FBpp0308508 | FBpp0078631 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Marcal1 (Marcal1) encodes an ATP-dependent DNA annealing helicase that recognizes single-stranded to double-stranded DNA transitions. It maintains genomic integrity through its roles in DNA repair, DNA replication, DNA recombination and gene expression; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. | 0.644 |
CG1407 | Patsas | FBpp0308508 | FBpp0423165 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | 0.567 |
CG1407 | Ppt1 | FBpp0308508 | FBpp0311872 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Palmitoyl-protein thioesterase 1 (Ppt1) encodes a lysosomal enzyme that removes palmitoyl groups from particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. | 0.494 |
CG1407 | Ppt2 | FBpp0308508 | FBpp0079801 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Palmitoyl-protein Thioesterase 2 (Ppt2) encodes a lysosomal enzyme that removes palmitoyl groups form particular target proteins during protein degradation within the lysosomal compartment. Palmitoylation is critical for the cellular localization and modulation of many signaling proteins. | 0.538 |
CG1407 | RPA3 | FBpp0308508 | FBpp0310183 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | Replication protein A3 (RPA3) encodes a protein involved in the maintenance of the neuronal stem cell population. | 0.527 |
CG1407 | mus302 | FBpp0308508 | FBpp0075105 | Protein-cysteine S-palmitoyltransferase activity. It is involved in the biological process described with: peptidyl-L-cysteine S-palmitoylation; protein targeting to membrane; protein palmitoylation. | RE72625p; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein ubiquitination; interstrand cross-link repair. | 0.517 |