node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6AP2 | Vha100-1 | FBpp0081458 | FBpp0084750 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | 0.993 |
ATP6AP2 | Vha13 | FBpp0081458 | FBpp0311933 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.974 |
ATP6AP2 | Vha26 | FBpp0081458 | FBpp0311965 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.984 |
ATP6AP2 | Vha44 | FBpp0081458 | FBpp0288470 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.947 |
ATP6AP2 | Vha55 | FBpp0081458 | FBpp0082139 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.994 |
ATP6AP2 | VhaAC39-1 | FBpp0081458 | FBpp0070584 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.998 |
ATP6AP2 | VhaAC39-2 | FBpp0081458 | FBpp0083793 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | Probable V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family. | 0.991 |
ATP6AP2 | VhaAC45 | FBpp0081458 | FBpp0087668 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit S1; Accessory subunit of the proton-transporting vacuolar (V)- ATPase protein pump, which is required for luminal acidification of secretory vesicles. | 0.999 |
ATP6AP2 | VhaPPA1-1 | FBpp0081458 | FBpp0082464 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching; Belongs to the V-ATPase proteolipid subunit family. | 0.994 |
ATP6AP2 | VhaSFD | FBpp0081458 | FBpp0080495 | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). | 0.994 |
Vha100-1 | ATP6AP2 | FBpp0084750 | FBpp0081458 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...] | 0.993 |
Vha100-1 | Vha13 | FBpp0084750 | FBpp0311933 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.983 |
Vha100-1 | Vha26 | FBpp0084750 | FBpp0311965 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.992 |
Vha100-1 | Vha44 | FBpp0084750 | FBpp0288470 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.980 |
Vha100-1 | Vha55 | FBpp0084750 | FBpp0082139 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.993 |
Vha100-1 | VhaAC39-1 | FBpp0084750 | FBpp0070584 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.997 |
Vha100-1 | VhaAC39-2 | FBpp0084750 | FBpp0083793 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | Probable V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family. | 0.988 |
Vha100-1 | VhaAC45 | FBpp0084750 | FBpp0087668 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit S1; Accessory subunit of the proton-transporting vacuolar (V)- ATPase protein pump, which is required for luminal acidification of secretory vesicles. | 0.979 |
Vha100-1 | VhaPPA1-1 | FBpp0084750 | FBpp0082464 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | Vacuolar H[+] ATPase PPA1 subunit 1 (VhaPPA1-1) encodes a protein involved in tracheal terminal branching; Belongs to the V-ATPase proteolipid subunit family. | 0.994 |
Vha100-1 | VhaSFD | FBpp0084750 | FBpp0080495 | Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development. | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). | 0.989 |