STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp4e2Cytochrome P450 4e2; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. (526 aa)    
Predicted Functional Partners:
CG18088
FI02830p; Catalytic activity. It is involved in the biological process described with: multicellular organism reproduction.
      
 0.673
CG42751
Uncharacterized protein.
      
 0.626
Cyp4e1
Probable cytochrome P450 4e1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.596
Cyp6a8
Cytochrome P450 6a8; Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.563
GstE3
Glutathione S transferase E3 (GstE3) encodes an enzyme involved in glutathione metabolic processes.
   
  
 0.546
CG6675
Uncharacterized protein, isoform B; Lipase activity; carboxylic ester hydrolase activity. It is involved in the biological process described with: lipid catabolic process.
    
 
 0.522
CG13323
IP04046p.
      
 0.491
Cyp6d5
Probable cytochrome P450 6d5; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.473
Cyp6w1
Probable cytochrome P450 6w1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.467
CG9360
RH17287p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.465
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.