STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1941RE04845p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process; triglyceride biosynthetic process. (352 aa)    
Predicted Functional Partners:
mdy
O-acyltransferase; Midway (mdy) encodes an acyl coenzyme A: diacylglycerol acyltransferase that functions in the formation of triglycerides. Lack of mdy leads to female sterility and impaired fat metabolism in larvae and adults.
   
 0.975
CG12746
RE23632p; Phosphatase activity; phosphatidate phosphatase activity. It is involved in the biological process described with: phospholipid metabolic process; phospholipid dephosphorylation; signal transduction.
   
 
 0.926
Mgat3
LD34806p; Transferase activity, transferring glycosyl groups; beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: protein N-linked glycosylation; N-acetylglucosamine metabolic process.
      
 0.912
Dgat2
Diacylglycerol O-acyltransferase activity; O-acyltransferase activity. It is involved in the biological process described with: lipid droplet organization; mesoderm development; lipid metabolic process; triglyceride biosynthetic process.
  
 
0.907
CG1946
IP08359p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: triglyceride biosynthetic process; lipid metabolic process.
  
 
0.906
CG34384
Diacylglycerol kinase eta; Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
     
 0.903
Dgk
Diacylglycerol kinase 1; Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.
     
 0.902
CG31140
Nucleic acid binding; NAD+ kinase activity; diacylglycerol kinase activity.
     
 0.902
rdgA
Retinal degeneration A (rdgA) encodes a diacylglycerol kinase that mediates the conversion of diacylglycerol to phosphatidic acid. It contributes to phospholipase C based signalling reactions, controlling ion channel activity and protein transport.
     
 0.902
Dgkepsilon
Diacyl glycerol kinase epsilon (Dgkepsilon) encodes a kinase that plays a key role in the metabolism of diacylglycerol by converting diacylglycerol into phosphatidic acid.
     
 0.901
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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