STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PxdPeroxidase (Pxd) encodes an enzyme that converts hydrogen peroxide to water and molecular oxygen, in the process oxidizing glutathione to glutathione disulfide. It is involved in the cellular response to oxidative stress; Belongs to the peroxidase family. XPO subfamily. (690 aa)    
Predicted Functional Partners:
CG5225
Uncharacterized protein; Extracellular matrix structural constituent. It is involved in the biological process described with: extracellular matrix organization.
      
 0.835
yellow-d2
Yellow-d2.
   
    0.751
zye
Zye; Structural constituent of chitin-based cuticle. It is involved in the biological process described with: cell-matrix adhesion; regulation of embryonic cell shape; actin filament organization; apical constriction.
   
    0.735
CG8306
Putative fatty acyl-CoA reductase CG8306; Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols.
      
 0.675
CG31268
Uncharacterized protein, isoform A; Extracellular matrix structural constituent. It is involved in the biological process described with: extracellular matrix organization.
      
 0.671
CG8839
LD05247p; Acylglycerol lipase activity; anandamide amidohydrolase activity.
      
 0.602
l(3)mbn
Protein lethal(3)malignant blood neoplasm 1; Lethal (3) malignant blood neoplasm (l(3)mbn) is a tumor suppressor gene with mutants showing abnormal proliferation of blood cells, differentiation of lamellocytes and melanotic nodule formation in the larva.
   
    0.572
tor
Tyrosine-protein kinase receptor torso; Probable receptor tyrosine kinase which is required for determination of anterior and posterior terminal structures in the embryo. During postembryonic development, involved in the initiation of metamorphosis probably by inducing the production of ecdysone in response to prothoracicotropic hormone Ptth. Binding to Ptth stimulates activation of canonical MAPK signaling leading to ERK phosphorylation (By similarity).
    
 
 0.540
CG8814
LD25952p; fatty-acyl-CoA binding.
      
 0.533
CG8907
FI19927p1; Rac guanyl-nucleotide exchange factor activity; actin binding. It is involved in the biological process described with: regulation of Rho protein signal transduction; Rho protein signal transduction; olfactory behavior.
      
 0.524
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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