node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG11658 | CG16721 | FBpp0075857 | FBpp0070786 | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | 0.694 |
CG11658 | CG6770 | FBpp0075857 | FBpp0079890 | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | 0.609 |
CG11658 | REPTOR | FBpp0075857 | FBpp0110093 | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Protein CREBRF homolog; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking [...] | 0.583 |
CG11658 | REPTOR-BP | FBpp0075857 | FBpp0088679 | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.613 |
CG11658 | unk | FBpp0075857 | FBpp0312602 | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | Unkempt (unk) encodes a highly conserved protein with roles in mRNA binding and ubiquitination. Together with the product of hdc, it acts downstream of the product of Mtor to regulate photoreceptor differentiation during eye development. | 0.664 |
CG16721 | CG11658 | FBpp0070786 | FBpp0075857 | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | 0.694 |
CG16721 | CG6770 | FBpp0070786 | FBpp0079890 | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | 0.708 |
CG16721 | REPTOR | FBpp0070786 | FBpp0110093 | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | Protein CREBRF homolog; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking [...] | 0.658 |
CG16721 | REPTOR-BP | FBpp0070786 | FBpp0088679 | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.673 |
CG16721 | unk | FBpp0070786 | FBpp0312602 | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | Unkempt (unk) encodes a highly conserved protein with roles in mRNA binding and ubiquitination. Together with the product of hdc, it acts downstream of the product of Mtor to regulate photoreceptor differentiation during eye development. | 0.795 |
CG3224 | REPTOR-BP | FBpp0070952 | FBpp0088679 | Zinc finger protein 593 homolog; Nucleic acid binding; zinc ion binding; ribosomal large subunit binding. It is involved in the biological process described with: ribosomal large subunit export from nucleus; Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.607 |
CG4282 | REPTOR-BP | FBpp0086288 | FBpp0088679 | LD21421p; DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of gene expression; regulation of transcription, DNA-templated. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.667 |
CG5885 | REPTOR-BP | FBpp0401486 | FBpp0088679 | LD05267p; It is involved in the biological process described with: SRP-dependent cotranslational protein targeting to membrane. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.616 |
CG6770 | CG11658 | FBpp0079890 | FBpp0075857 | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | 0.609 |
CG6770 | CG16721 | FBpp0079890 | FBpp0070786 | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | 0.708 |
CG6770 | REPTOR | FBpp0079890 | FBpp0110093 | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | Protein CREBRF homolog; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking [...] | 0.495 |
CG6770 | REPTOR-BP | FBpp0079890 | FBpp0088679 | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | REPTOR-binding partner; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts to enhance the binding of the transcriptional activator REPTOR to the regulatory sequences of target genes. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphory [...] | 0.571 |
CG6770 | unk | FBpp0079890 | FBpp0312602 | RH17958p; It is involved in the biological process described with: negative regulation of cell cycle; negative regulation of cell population proliferation; regulation of transcription by RNA polymerase II. | Unkempt (unk) encodes a highly conserved protein with roles in mRNA binding and ubiquitination. Together with the product of hdc, it acts downstream of the product of Mtor to regulate photoreceptor differentiation during eye development. | 0.626 |
REPTOR | CG11658 | FBpp0110093 | FBpp0075857 | Protein CREBRF homolog; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking [...] | LD30288p; It is involved in the biological process described with: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. | 0.583 |
REPTOR | CG16721 | FBpp0110093 | FBpp0070786 | Protein CREBRF homolog; Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking [...] | LD23868p; It is involved in the biological process described with: cAMP-mediated signaling; signal transduction. | 0.658 |