node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG42458 | bsh | FBpp0289481 | FBpp0088920 | RRM domain-containing protein; mRNA binding; RNA binding. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.478 |
CG6523 | bsh | FBpp0080044 | FBpp0088920 | LD40224p; Protein disulfide oxidoreductase activity; electron transfer activity. It is involved in the biological process described with: cellular iron ion homeostasis; cell redox homeostasis. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.463 |
Ets65A | bsh | FBpp0312433 | FBpp0088920 | DNA-binding protein D-ETS-3; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; cell differentiation; regulation of transcription by RNA polymerase II; Belongs to the ETS family. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.404 |
Hmx | bsh | FBpp0303412 | FBpp0088920 | Homeobox protein Hmx; Transcription factor involved in specification of neuronal cell types; Belongs to the HMX homeobox family. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.423 |
Vsx1 | bsh | FBpp0309431 | FBpp0088920 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.402 |
Vsx1 | hth | FBpp0309431 | FBpp0081732 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Homeobox protein homothorax; All isoforms are required for patterning of the embryonic cuticle. Acts with exd to delimit the eye field and prevent inappropriate eye development. Isoforms that carry the homeodomain are required for proper localization of chordotonal organs within the peripheral nervous system and antennal identity; required to activate antennal-specific genes, such as sal and to repress the leg-like expression of dac. Necessary for the nuclear localization of the essential HOX cofactor, extradenticle (exd). Both necessary and sufficient for inner photoreceptors to adopt [...] | 0.653 |
Vsx1 | slp1 | FBpp0309431 | FBpp0077188 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Sloppy paired 1 (slp1) encodes a transcription factor of the fork-head family that functions by interacting with the corepressor encoded by gro. The product of slp1 regulates a wide variety of developmental processes including embryonic segmentation, ventral fate specification in the retina, and temporal patterning of the neuroblasts that produce medulla neurons. | 0.455 |
Vsx1 | svp | FBpp0309431 | FBpp0082035 | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | Steroid receptor seven-up, isoform A; Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC- 2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs). Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.490 |
bsh | CG42458 | FBpp0088920 | FBpp0289481 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | RRM domain-containing protein; mRNA binding; RNA binding. | 0.478 |
bsh | CG6523 | FBpp0088920 | FBpp0080044 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | LD40224p; Protein disulfide oxidoreductase activity; electron transfer activity. It is involved in the biological process described with: cellular iron ion homeostasis; cell redox homeostasis. | 0.463 |
bsh | Ets65A | FBpp0088920 | FBpp0312433 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | DNA-binding protein D-ETS-3; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; cell differentiation; regulation of transcription by RNA polymerase II; Belongs to the ETS family. | 0.404 |
bsh | Hmx | FBpp0088920 | FBpp0303412 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Homeobox protein Hmx; Transcription factor involved in specification of neuronal cell types; Belongs to the HMX homeobox family. | 0.423 |
bsh | Vsx1 | FBpp0088920 | FBpp0309431 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | 0.402 |
bsh | chp | FBpp0088920 | FBpp0303134 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Chaoptin; Required for photoreceptor cell morphogenesis. Mediates homophilic cellular adhesion; Belongs to the chaoptin family. | 0.491 |
bsh | hth | FBpp0088920 | FBpp0081732 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Homeobox protein homothorax; All isoforms are required for patterning of the embryonic cuticle. Acts with exd to delimit the eye field and prevent inappropriate eye development. Isoforms that carry the homeodomain are required for proper localization of chordotonal organs within the peripheral nervous system and antennal identity; required to activate antennal-specific genes, such as sal and to repress the leg-like expression of dac. Necessary for the nuclear localization of the essential HOX cofactor, extradenticle (exd). Both necessary and sufficient for inner photoreceptors to adopt [...] | 0.607 |
bsh | pan | FBpp0088920 | FBpp0111569 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Protein pangolin, isoform J; Pangolin (pan) encodes an HMG-domain transcription factor that is a key component of the canonical Wingless signaling pathway. It toggles between acting as a transcriptional repressor (when bound to the product of gro) and activator (when bound to the product of arm) to promote cell fate specification. | 0.911 |
bsh | slp1 | FBpp0088920 | FBpp0077188 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Sloppy paired 1 (slp1) encodes a transcription factor of the fork-head family that functions by interacting with the corepressor encoded by gro. The product of slp1 regulates a wide variety of developmental processes including embryonic segmentation, ventral fate specification in the retina, and temporal patterning of the neuroblasts that produce medulla neurons. | 0.505 |
bsh | svp | FBpp0088920 | FBpp0082035 | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | Steroid receptor seven-up, isoform A; Receptor that is required in photoreceptors R1, R3, R4 and R6 during eye development; generation of the ganglion mother cell-2 (GMC- 2) fate in the nb7-3 lineage, coinciding with the transition in the expression of HB to KR in the neuroblasts (NBs). Belongs to the nuclear hormone receptor family. NR2 subfamily. | 0.642 |
chp | bsh | FBpp0303134 | FBpp0088920 | Chaoptin; Required for photoreceptor cell morphogenesis. Mediates homophilic cellular adhesion; Belongs to the chaoptin family. | Brain-specific homeobox protein; DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. | 0.491 |
hth | Vsx1 | FBpp0081732 | FBpp0309431 | Homeobox protein homothorax; All isoforms are required for patterning of the embryonic cuticle. Acts with exd to delimit the eye field and prevent inappropriate eye development. Isoforms that carry the homeodomain are required for proper localization of chordotonal organs within the peripheral nervous system and antennal identity; required to activate antennal-specific genes, such as sal and to repress the leg-like expression of dac. Necessary for the nuclear localization of the essential HOX cofactor, extradenticle (exd). Both necessary and sufficient for inner photoreceptors to adopt [...] | Visual system homeobox 1 (Vsx1) encodes a transcription factor involved in the development of the visual-system. | 0.653 |