STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPMultidrug-Resistance like protein 1, isoform A; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport; renal tubular secretion; response to toxic substance; anion transmembrane transport. (1549 aa)    
Predicted Functional Partners:
CG30344
GH23453p; Transporter activity. It is involved in the biological process described with: response to toxic substance; renal tubular secretion; transmembrane transport.
   
  
 0.839
Oatp58Dc
Solute carrier organic anion transporter family member; Organic anion transporting polypeptide 58Dc (Oatp58Dc) encodes a membrane transporter implicated in renal elimination of organic compounds including ouabain and methotrexate. In the perineural glia of the blood brain barrier, the product of Oatp58Dc protects the brain from potentially toxic organic anions in the hemolymph.
      
 0.670
CG17646
SD03967p; ATPase activity; ATP binding; ATPase-coupled transmembrane transporter activity. It is involved in the biological process described with: triglyceride metabolic process; transmembrane transport.
  
 
 0.664
Lcp1
Larval cuticle protein 1; Component of the larval cuticle.
      
 0.606
bw
Brown (bw) encodes a member of the traffic ATPase (or ABC) family of membrane transporters. It is believed to heterodimerize with the product of w. bw and w are necessary to import guanine, a precursor for the red pteridine pigments, into pigment cells of the eyes, Malpighian tubules and testis sheath.
  
 0.567
CG7806
LD42916p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport.
  
 
0.549
rdog
Red dog mine, isoform A; ATP binding; ATPase-coupled transmembrane transporter activity; ATPase activity. It is involved in the biological process described with: transmembrane transport.
  
 
0.532
CG31121
FI03229p; ATPase-coupled transmembrane transporter activity; ATP binding; ATPase activity. It is involved in the biological process described with: transmembrane transport.
  
 0.529
Cyp12d1-p
Probable cytochrome P450 12d1 proximal, mitochondrial; Cyp12d1-p (Cyp12d1-p) encodes a protein involved in the response to the insecticide dichlorodiphenyltrichloroethane (DDT).
   
 
 0.523
Sk2
Sphingosine kinase 2 (Sk2) encodes a D-erythro-sphingosine kinase that contributes to sphingolipid metabolism, flight performance and ovulation.
      
 0.522
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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