STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rnp4FRNA-binding protein 4F (Rnp4F) encodes an essential evolutionarily-conserved RNA-binding protein. Rnp4F gene expression is post-transcriptionally regulated by interaction with a stable stem-loop structure in the 5'-UTR of the mRNA with trans-acting factors. (941 aa)    
Predicted Functional Partners:
CG17768
U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family.
    
 
 0.993
CG2021
U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 
 0.992
CG10418
U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 
 0.992
CG9344
RE43665p; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5.
    
 
 0.991
CG6610
U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA; Belongs to the snRNP Sm proteins family.
   
 
 0.991
LSm7
Like Sm 7, isoform A; RNA binding. It is involved in the biological process described with: nuclear-transcribed mRNA catabolic process; mRNA splicing, via spliceosome.
   
 
 0.991
LSm3
U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 
 0.955
CG33108
UPF0692 protein CG33108; Belongs to the UPF0692 family.
    
 
 0.910
Prp3
Precursor RNA processing 3 (Prp3) encodes a protein that regulates chromatin silencing.
   
 
 0.885
U4-U6-60K
U4-U6 small nuclear riboprotein factor 60K; U4 snRNA binding; U6 snRNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome.
   
 
 0.861
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.