STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CheA56aChemosensory protein A 56a; It is involved in the biological process described with: sensory perception of chemical stimulus. (180 aa)    
Predicted Functional Partners:
Npc1b
NPC intracellular cholesterol transporter 1 homolog 1b; Important for cholesterol absorption at the midgut epithelium. Acts only in the early steps of sterol absorption, prior to Npc1a-dependent intracellular sterol trafficking. Belongs to the patched family.
    
 
 0.446
Npc1a
Niemann-Pick type C-1a (Npc1a) encodes a cholesterol trafficking protein that contributes to sterol and ecdysone metabolism. It is involved in sperm individualization.
    
 
 0.446
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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