Alpha-actinin, sarcomeric; Alpha actinin (Actn) encodes an actin cross-linking protein with muscle and non-muscle specific isoforms, which are produced by alternative spicing. The muscle isoform has a role in muscle development while the non-muscle isoform localizes to ovarian ring canals and has a role in cytoskeletal remodeling of follicle cells; Belongs to the alpha-actinin family.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Alpha-actinin, sarcomeric; Alpha actinin (Actn) encodes an actin cross-linking protein with muscle and non-muscle specific isoforms, which are produced by alternative spicing. The muscle isoform has a role in muscle development while the non-muscle isoform localizes to ovarian ring canals and has a role in cytoskeletal remodeling of follicle cells; Belongs to the alpha-actinin family.

Parvin, isoform A; Parvin (parvin) encodes a Calponin-homology protein that, together with the products of Ilk and stck, reinforces integrin-matrix adhesion at muscle attachment sites in the developing embryo. The product of parvin contributes to cell adhesion and actin cytoskeleton organisation in muscles, wing and eye epithelial cells.

Inositol-1-monophosphatase; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Sarcoglycan alpha, isoform C; Structural constituent of muscle; calcium ion binding.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Sarcoglycan beta (Scgbeta) encodes a component of the sarcoglycan complex, which is a sub-complex of the dystrophin glycoprotein complex. The product of Scgbeta negatively regulates the EGFR signaling pathway in eye imaginal discs.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Gamma/delta-sarcoglycan-like protein SCG-GAMMA/DELTA; Sarcoglycan delta (Scgdelta) encodes a transmembrane protein that is required for normal muscle structure and function. It contributes to sarcomere organization and heart contraction.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Syntrophin-like 1, isoform B; Syntrophin-like 1 (Syn1) encodes an adaptor protein associated with the Dystrophin glycoprotein complex that recruits different signaling components, including the product of Nos in neurons. Dystrophin-Syn1-neuronal Nos signaling via histone modifications regulates gene expression, including expression of miRNAs, and adapts cellular homeostasis, which is compromised under stress and dystrophic conditions.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Syntrophin-like 2 (Syn2) encodes a component of the dystrophin glycoprotein complex (DGC) that may act in molecular scaffolding, recruiting signaling proteins to membranes and the DGC. It is required for locomotion and is involved in regulation of synaptic morphology.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Sarcoglycan alpha, isoform C; Structural constituent of muscle; calcium ion binding.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Sarcoglycan beta (Scgbeta) encodes a component of the sarcoglycan complex, which is a sub-complex of the dystrophin glycoprotein complex. The product of Scgbeta negatively regulates the EGFR signaling pathway in eye imaginal discs.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Gamma/delta-sarcoglycan-like protein SCG-GAMMA/DELTA; Sarcoglycan delta (Scgdelta) encodes a transmembrane protein that is required for normal muscle structure and function. It contributes to sarcomere organization and heart contraction.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Syntrophin-like 1, isoform B; Syntrophin-like 1 (Syn1) encodes an adaptor protein associated with the Dystrophin glycoprotein complex that recruits different signaling components, including the product of Nos in neurons. Dystrophin-Syn1-neuronal Nos signaling via histone modifications regulates gene expression, including expression of miRNAs, and adapts cellular homeostasis, which is compromised under stress and dystrophic conditions.

Dystrobrevin, isoform F; Zinc ion binding; structural constituent of muscle. It is involved in the biological process described with: synaptic signaling.

Syntrophin-like 2 (Syn2) encodes a component of the dystrophin glycoprotein complex (DGC) that may act in molecular scaffolding, recruiting signaling proteins to membranes and the DGC. It is required for locomotion and is involved in regulation of synaptic morphology.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Alpha-actinin, sarcomeric; Alpha actinin (Actn) encodes an actin cross-linking protein with muscle and non-muscle specific isoforms, which are produced by alternative spicing. The muscle isoform has a role in muscle development while the non-muscle isoform localizes to ovarian ring canals and has a role in cytoskeletal remodeling of follicle cells; Belongs to the alpha-actinin family.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Inositol-1-monophosphatase; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.

Dystrophin, isoforms A/C/F/G/H; Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane.

Dystroglycan, isoform D; Dystroglycan (Dg) encodes a major non-integrin extracellular matrix (ECM) receptor that connects the ECM to the actin cytoskeleton. It regulates animal survival and temperature preference, muscle integrity, myotendinous and neuromuscular junction formation and function, nervous system development, axon pathfinding, rhabdomere differentiation, neuronal stem cell division and epithelial polarity.