node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
14-3-3epsilon | Gp93 | FBpp0082987 | FBpp0084623 | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 0.548 |
14-3-3epsilon | Hsf | FBpp0082987 | FBpp0110266 | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. | 0.821 |
14-3-3epsilon | Hsp83 | FBpp0082987 | FBpp0305095 | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.465 |
14-3-3epsilon | eEF1alpha1 | FBpp0082987 | FBpp0304260 | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.517 |
14-3-3epsilon | eEF1alpha2 | FBpp0082987 | FBpp0085193 | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.458 |
CG5446 | Hsf | FBpp0305307 | FBpp0110266 | GEO09660p1; Transcription corepressor activity. It is involved in the biological process described with: cellular heat acclimation. | Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. | 0.827 |
CG5446 | Hsp70Bb | FBpp0305307 | FBpp0082106 | GEO09660p1; Transcription corepressor activity. It is involved in the biological process described with: cellular heat acclimation. | Heat-shock-protein-70Bb (Hsp70Bb) encodes a protein involved in response to hypoxia heat shock and. | 0.432 |
CG5446 | Hsp83 | FBpp0305307 | FBpp0305095 | GEO09660p1; Transcription corepressor activity. It is involved in the biological process described with: cellular heat acclimation. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.449 |
Gp93 | 14-3-3epsilon | FBpp0084623 | FBpp0082987 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 14-3-3epsilon (14-3-3epsilon) encodes an acidic protein that preferentially heterodimerizes with other members of the family but also can homodimerize. It functions in multiple signaling pathways, most prominently in the Ras/MAPK cascade. It is involved in embryonic hatching, germ cell migration, gonad formation, wing venation and eye development; Belongs to the 14-3-3 family. | 0.548 |
Gp93 | HDAC6 | FBpp0084623 | FBpp0303431 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Histone deacetylase 6, isoform G; Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. | 0.896 |
Gp93 | Hsf | FBpp0084623 | FBpp0110266 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. | 0.924 |
Gp93 | Hsp70Bb | FBpp0084623 | FBpp0082106 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Heat-shock-protein-70Bb (Hsp70Bb) encodes a protein involved in response to hypoxia heat shock and. | 0.712 |
Gp93 | Hsp83 | FBpp0084623 | FBpp0305095 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.468 |
Gp93 | TER94 | FBpp0084623 | FBpp0111818 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...] | 0.672 |
Gp93 | eEF1alpha1 | FBpp0084623 | FBpp0304260 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.635 |
Gp93 | eEF1alpha2 | FBpp0084623 | FBpp0085193 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.644 |
Gp93 | p23 | FBpp0084623 | FBpp0081560 | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | Uncharacterized protein CG16817; prostaglandin-E synthase activity; Hsp90 protein binding; chaperone binding. It is involved in the biological process described with: protein folding; positive regulation of small RNA loading onto RISC; chaperone-mediated protein complex assembly; Belongs to the p23/wos2 family. | 0.908 |
HDAC6 | Gp93 | FBpp0303431 | FBpp0084623 | Histone deacetylase 6, isoform G; Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. | Glycoprotein 93 (Gp93) encodes a heat shock protein Hsp90 family member that is involved in midgut development. | 0.896 |
HDAC6 | Hsf | FBpp0303431 | FBpp0110266 | Histone deacetylase 6, isoform G; Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. | Heat shock factor protein; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. | 0.820 |
HDAC6 | Hsp83 | FBpp0303431 | FBpp0305095 | Histone deacetylase 6, isoform G; Histone deacetylase 6 (HDAC6) encodes a cytosolic deacetylase that functions as a key modulator of proteostasis by mediating ubiquitin-proteasomal and lysosomal degradation of native and/or misfolded proteins. | Heat shock protein 83; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Together with Hop and piwi, mediates canalization, also known as develop [...] | 0.654 |