STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cht10Probable chitinase 10; Chitinase activity; chitin binding. It is involved in the biological process described with: carbohydrate metabolic process; chitin catabolic process. (2286 aa)    
Predicted Functional Partners:
CG6218
GH07590p; N-acetylglucosamine kinase activity. It is involved in the biological process described with: carbohydrate phosphorylation.
     
 0.940
Hexo2
Beta-hexosaminidase; Hexosaminidase 2 (Hexo2) encodes a beta-N-acetylglucosaminidase involved in carbohydrate metabolism.
    
 0.727
Hexo1
Beta-hexosaminidase; Hexosaminidase 1 (Hexo1) encodes a beta-N-acetylglucosaminidase involved in protein deglycosylation and rhodopsin biosynthesis.
    
 0.705
Chs2
Chitin synthase activity. It is involved in the biological process described with: cuticle chitin biosynthetic process.
     
 0.701
CG30440
LD43457p; Rho guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: positive regulation of Rho protein signal transduction.
   
    0.632
kkv
Krotzkopf verkehrt (kkv) encodes a membrane-inserted glycosyltransferase family 2 chitin synthase that uses GlcNAc to produce the polysaccharide chitin, which is extruded to the differentiating cuticle and tracheal system (tracheal cuticle, tube diameter regulation and gas filling).
   
  
 0.622
Amy-p
Alpha-amylase B; Amylase proximal (Amy-p) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
      
 0.537
CG6262
Trehalase; Alpha,alpha-trehalase activity. It is involved in the biological process described with: trehalose metabolic process.
      
 0.512
Treh
Trehalase (Treh) encodes an enzyme that hydrolyzes the the disaccharide trehalose to two molecules of glucose in either the cytoplasm or the extracellular space; Belongs to the glycosyl hydrolase 37 family.
      
 0.511
Amy-d
Amylase distal (Amy-d) encodes one of three amylases encoded in the Drosophila genome. It is a digestive enzyme required for the hydrolysis of dietary starch.
      
 0.505
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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