node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Antp | hh | FBpp0081162 | FBpp0099945 | Homeotic protein antennapedia; Antennapedia (Antp) is the distal-most member of the Antennapedia complex; one of two Hox gene complexes. Antp encodes a sequence-specific homeodomain transcription factor, which is part of a developmental regulatory system that specifies segmental identity in the pro- and mesothorax. In adults Antp loss of function is associated with a transformation of leg into antenna while ectopic expression in the head is associated with antenna to leg and eye to wing transformations. | Protein hedgehog C-product; Intercellular signal essential for a variety of patterning events during development. Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu). Essential component of a signaling pathway which regulates the Duox-dependent gut immune r [...] | 0.641 |
Antp | kn | FBpp0081162 | FBpp0111722 | Homeotic protein antennapedia; Antennapedia (Antp) is the distal-most member of the Antennapedia complex; one of two Hox gene complexes. Antp encodes a sequence-specific homeodomain transcription factor, which is part of a developmental regulatory system that specifies segmental identity in the pro- and mesothorax. In adults Antp loss of function is associated with a transformation of leg into antenna while ectopic expression in the head is associated with antenna to leg and eye to wing transformations. | Transcription factor collier; May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment. | 0.637 |
CG12010 | CG4603 | FBpp0072937 | FBpp0303184 | Uncharacterized protein; ATPase activity; ATP binding. | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | 0.810 |
CG12010 | Plap | FBpp0072937 | FBpp0310466 | Uncharacterized protein; ATPase activity; ATP binding. | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | 0.842 |
CG12010 | Ufd1-like | FBpp0072937 | FBpp0075952 | Uncharacterized protein; ATPase activity; ATP binding. | Ubiquitin fusion degradation protein 1 homolog; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway; Belongs to the UFD1 family. | 0.860 |
CG12010 | kn | FBpp0072937 | FBpp0111722 | Uncharacterized protein; ATPase activity; ATP binding. | Transcription factor collier; May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment. | 0.580 |
CG4603 | CG12010 | FBpp0303184 | FBpp0072937 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | Uncharacterized protein; ATPase activity; ATP binding. | 0.810 |
CG4603 | CG5776 | FBpp0303184 | FBpp0302957 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | LD25466p; ATP binding; ATPase activity. | 0.810 |
CG4603 | Plap | FBpp0303184 | FBpp0310466 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | 0.991 |
CG4603 | TER94 | FBpp0303184 | FBpp0111818 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...] | 0.984 |
CG4603 | Ufd1-like | FBpp0303184 | FBpp0075952 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | Ubiquitin fusion degradation protein 1 homolog; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway; Belongs to the UFD1 family. | 0.988 |
CG4603 | kn | FBpp0303184 | FBpp0111722 | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | Transcription factor collier; May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment. | 0.866 |
CG5776 | CG4603 | FBpp0302957 | FBpp0303184 | LD25466p; ATP binding; ATPase activity. | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | 0.810 |
CG5776 | Plap | FBpp0302957 | FBpp0310466 | LD25466p; ATP binding; ATPase activity. | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | 0.843 |
CG5776 | Ufd1-like | FBpp0302957 | FBpp0075952 | LD25466p; ATP binding; ATPase activity. | Ubiquitin fusion degradation protein 1 homolog; Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway; Belongs to the UFD1 family. | 0.860 |
CG5776 | kn | FBpp0302957 | FBpp0111722 | LD25466p; ATP binding; ATPase activity. | Transcription factor collier; May act as a 'second-level regulator' of head patterning. Required for establishment of the PS(-1)/PS0 parasegmental border and formation of the intercalary segment. Required for expression of the segment polarity genes hedgehog, engrailed and wingless, and the segment-identity genes CAP and collar in the intercalary segment. Required at the onset of the gastrulation for the correct formation of the mandibular segment. | 0.580 |
Plap | CG12010 | FBpp0310466 | FBpp0072937 | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | Uncharacterized protein; ATPase activity; ATP binding. | 0.842 |
Plap | CG4603 | FBpp0310466 | FBpp0303184 | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. | 0.991 |
Plap | CG5776 | FBpp0310466 | FBpp0302957 | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | LD25466p; ATP binding; ATPase activity. | 0.843 |
Plap | TER94 | FBpp0310466 | FBpp0111818 | Phospholipase A2 activator protein, isoform A; Ubiquitin binding. It is involved in the biological process described with: proteasome-mediated ubiquitin-dependent protein catabolic process; ubiquitin recycling. | Transitional endoplasmic reticulum ATPase TER94; Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. Involved in the ubiquitin-proteasome system. Important for oskar mRNA localization and/ [...] | 0.928 |