STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG12004IP17403p; Carbohydrate binding. It is involved in the biological process described with: defense response to fungus; synaptic target recognition. (486 aa)    
Predicted Functional Partners:
Atg8a
Autophagy-related 8a (Atg8a) encodes a ubiquitin-like protein that is conjugated to phosphatidylethanolamine, and this lipid modification anchors it into the membrane of forming and completed autophagosomes. Atg8a product has roles in autophagosome formation, maintaining neuromuscular function and normal lifespan.
   
 
 0.853
Atg8b
Autophagy-related 8b, isoform A; Microtubule binding; protein tag; ubiquitin protein ligase binding; GABA receptor binding. It is involved in the biological process described with: macroautophagy; autophagosome maturation; cellular response to nitrogen starvation; autophagy of mitochondrion; autophagosome assembly.
    
 
 0.852
CG6041
LP11750p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
      
 0.668
CG33090
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide.
      
 0.663
CG12744
Uncharacterized zinc finger protein CG12744; May be involved in transcriptional regulation.
      
 0.663
CG6048
FI06405p; Serine-type endopeptidase activity. It is involved in the biological process described with: regulation of terminal button organization; proteolysis.
      
 0.662
CG6495
BcDNA.GH10711.
      
 0.627
fs(1)M3
Female sterile (1) M3 (fs(1)M3) encodes a protein that is required, along with the products of fs(1)N and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation.
      
 0.609
coro
Coronin; Actin filament binding. It is involved in the biological process described with: defense response to fungus; actin filament organization; adult somatic muscle development; Belongs to the WD repeat coronin family.
   
  
 0.543
dsd
Distracted, isoform B; It is involved in the biological process described with: animal organ morphogenesis; synaptic target recognition; tissue development.
   
  
 0.535
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.