node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atg6 | Dsp1 | FBpp0083975 | FBpp0288398 | Beclin-1-like protein; Autophagy-related 6 (Atg6) encodes a component of the Vps34 complex that is required for the formation of PI3P, and functions in vesicle trafficking including autophagy and endocytosis. | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | 0.932 |
Atg6 | Myd88 | FBpp0083975 | FBpp0305215 | Beclin-1-like protein; Autophagy-related 6 (Atg6) encodes a component of the Vps34 complex that is required for the formation of PI3P, and functions in vesicle trafficking including autophagy and endocytosis. | Myd88 (Myd88) encodes an adaptor protein involved in in the Toll pathway functioning downstream of the product of Tl and upstream of the product of tub. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides. | 0.754 |
Bap111 | Dsp1 | FBpp0071235 | FBpp0288398 | Brahma associated protein 111kD (Bap111) encodes a protein important for Brahma complex function. It is involved in chromatin remodeling and transcription induction. | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | 0.721 |
Bap111 | HDAC1 | FBpp0071235 | FBpp0073173 | Brahma associated protein 111kD (Bap111) encodes a protein important for Brahma complex function. It is involved in chromatin remodeling and transcription induction. | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | 0.562 |
Calr | Dsp1 | FBpp0306685 | FBpp0288398 | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | 0.526 |
Dsp1 | Atg6 | FBpp0288398 | FBpp0083975 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Beclin-1-like protein; Autophagy-related 6 (Atg6) encodes a component of the Vps34 complex that is required for the formation of PI3P, and functions in vesicle trafficking including autophagy and endocytosis. | 0.932 |
Dsp1 | Bap111 | FBpp0288398 | FBpp0071235 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Brahma associated protein 111kD (Bap111) encodes a protein important for Brahma complex function. It is involved in chromatin remodeling and transcription induction. | 0.721 |
Dsp1 | Calr | FBpp0288398 | FBpp0306685 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). | 0.526 |
Dsp1 | Gcn5 | FBpp0288398 | FBpp0075701 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | 0.553 |
Dsp1 | HDAC1 | FBpp0288398 | FBpp0073173 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | 0.879 |
Dsp1 | His2Av | FBpp0288398 | FBpp0306426 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Histone H2A.v; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repre [...] | 0.581 |
Dsp1 | Jra | FBpp0288398 | FBpp0303456 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Plays a role in dorsal closure. Belongs to the bZIP family. Jun subfamily. | 0.895 |
Dsp1 | Myd88 | FBpp0288398 | FBpp0305215 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Myd88 (Myd88) encodes an adaptor protein involved in in the Toll pathway functioning downstream of the product of Tl and upstream of the product of tub. Toll pathway is a signaling cascade that plays a key role in various developmental and immune processes, notably embryonic dorsoventral patterning and regulation of antimicrobial peptides. | 0.535 |
Dsp1 | Stat92E | FBpp0288398 | FBpp0306651 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Signal-transducer and activator of transcription protein at 92E (Stat92E) encodes a transcription factor that shuttles between the cytosol and nucleus and functions in the JAK/STAT pathway. Its roles include proliferation, growth control, organismal metabolism, cell competition, stem cell self-renewal, immunity and developmental patterning. | 0.882 |
Dsp1 | kay | FBpp0288398 | FBpp0288515 | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | Transcription factor kayak, isoforms A/B/F; Developmentally regulated transcription factor AP-1 binds and recognizes the enhancer DNA sequence: 5'-TGA[CG]TCA-3'. May play a role in the function or determination of a particular subset of cells in the developing embryo. It is able to carry out its function either independently of or in conjunction with Jra. Belongs to the bZIP family. Fos subfamily. | 0.814 |
Gcn5 | Dsp1 | FBpp0075701 | FBpp0288398 | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | High mobility group protein DSP1; Binds preferentially single-stranded DNA and unwinds double- stranded DNA. | 0.553 |
Gcn5 | HDAC1 | FBpp0075701 | FBpp0073173 | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | Histone deacetylase HDAC1; Catalyzes the deacetylation of lysine residues on the N- terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones. Involved in position-effect variegation (PEV). In the larval brain, part of a regulatory network including the transcript [...] | 0.967 |
Gcn5 | His2Av | FBpp0075701 | FBpp0306426 | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | Histone H2A.v; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repre [...] | 0.950 |
Gcn5 | Jra | FBpp0075701 | FBpp0303456 | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Plays a role in dorsal closure. Belongs to the bZIP family. Jun subfamily. | 0.709 |
Gcn5 | Stat92E | FBpp0075701 | FBpp0306651 | Gcn5 acetyltransferase (Gcn5) encodes a lysine acetyltransferase subunit of several chromatin modifying complexes. It contributes to oogenesis and metamorphosis. | Signal-transducer and activator of transcription protein at 92E (Stat92E) encodes a transcription factor that shuttles between the cytosol and nucleus and functions in the JAK/STAT pathway. Its roles include proliferation, growth control, organismal metabolism, cell competition, stem cell self-renewal, immunity and developmental patterning. | 0.523 |