node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG1074 | CG11447 | FBpp0078565 | FBpp0083225 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.406 |
CG1074 | CG33172 | FBpp0078565 | FBpp0300435 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | 0.770 |
CG1074 | CG8939 | FBpp0078565 | FBpp0073943 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. | 0.659 |
CG1074 | RpI1 | FBpp0078565 | FBpp0086640 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | DNA-directed RNA polymerase I subunit RPA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation o [...] | 0.524 |
CG1074 | THADA | FBpp0078565 | FBpp0288416 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | Thyroid adenoma-associated protein homolog; Plays a key role in energy homeostasis by regulating the balance between energy storage and heat production. Functions by negatively regulating Ca(2+) signaling pathways that are involved in heat production and maintaining correct lipid storage in the fat body. Regulates Ca(2+) signaling pathways by reducing the activity of the calcium-transporting ATPase SERCA possibly by promoting uncoupling of SERCA ATP hydrolysis from calcium pumping. May also function in the nervous system to control feeding behavior. | 0.503 |
CG1074 | Trm7-32 | FBpp0078565 | FBpp0082832 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 1; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.609 |
CG1074 | Trm7-34 | FBpp0078565 | FBpp0083432 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 2; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.592 |
CG1074 | wuho | FBpp0078565 | FBpp0070862 | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis. | 0.814 |
CG11447 | CG1074 | FBpp0083225 | FBpp0078565 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | 0.406 |
CG11447 | CG33172 | FBpp0083225 | FBpp0300435 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | 0.932 |
CG11447 | THADA | FBpp0083225 | FBpp0288416 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | Thyroid adenoma-associated protein homolog; Plays a key role in energy homeostasis by regulating the balance between energy storage and heat production. Functions by negatively regulating Ca(2+) signaling pathways that are involved in heat production and maintaining correct lipid storage in the fat body. Regulates Ca(2+) signaling pathways by reducing the activity of the calcium-transporting ATPase SERCA possibly by promoting uncoupling of SERCA ATP hydrolysis from calcium pumping. May also function in the nervous system to control feeding behavior. | 0.540 |
CG11447 | wuho | FBpp0083225 | FBpp0070862 | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis. | 0.559 |
CG33172 | CG1074 | FBpp0300435 | FBpp0078565 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | SD03208p; Methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; nucleic acid binding. It is involved in the biological process described with: methylation. | 0.770 |
CG33172 | CG11447 | FBpp0300435 | FBpp0083225 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1579 (Um1579) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.932 |
CG33172 | CG8939 | FBpp0300435 | FBpp0073943 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. | 0.837 |
CG33172 | RpI1 | FBpp0300435 | FBpp0086640 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | DNA-directed RNA polymerase I subunit RPA1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation o [...] | 0.531 |
CG33172 | THADA | FBpp0300435 | FBpp0288416 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | Thyroid adenoma-associated protein homolog; Plays a key role in energy homeostasis by regulating the balance between energy storage and heat production. Functions by negatively regulating Ca(2+) signaling pathways that are involved in heat production and maintaining correct lipid storage in the fat body. Regulates Ca(2+) signaling pathways by reducing the activity of the calcium-transporting ATPase SERCA possibly by promoting uncoupling of SERCA ATP hydrolysis from calcium pumping. May also function in the nervous system to control feeding behavior. | 0.871 |
CG33172 | Trm7-32 | FBpp0300435 | FBpp0082832 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 1; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.981 |
CG33172 | Trm7-34 | FBpp0300435 | FBpp0083432 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase 2; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.986 |
CG33172 | wuho | FBpp0300435 | FBpp0070862 | MIP10235p; RNA binding. It is involved in the biological process described with: negative regulation of cell population proliferation. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Required during gametogenesis. | 0.694 |