STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
l(1)G0196Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1846 aa)    
Predicted Functional Partners:
CG11068
AT20767p.
      
 0.835
CG6602
Uncharacterized protein.
      
 0.790
CG10082
Kinase activity; inositol hexakisphosphate kinase activity. It is involved in the biological process described with: phosphatidylinositol phosphorylation; inositol phosphate biosynthetic process; Belongs to the inositol phosphokinase (IPK) family.
    
 
 0.672
CG9044
Uncharacterized protein, isoform C; Protein kinase binding. It is involved in the biological process described with: protein localization.
      
 0.669
CG6983
GM13032p.
      
 0.665
CG8740
Uncharacterized protein, isoform D.
      
 0.660
CG2691
RRP12-like protein; It is involved in the biological process described with: rRNA processing.
      
 0.660
CG11417
EG:8D8.4 protein; RNA binding. It is involved in the biological process described with: rRNA processing.
      
 0.627
CG6418
LD32732p; ATP binding; helicase activity; RNA binding; RNA helicase activity; Belongs to the DEAD box helicase family.
      
 0.609
CG31678
LD18032p.
      
 0.607
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.