STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ndae1Na[+]-driven anion exchanger 1 (Ndae1) encodes an intrinsic membrane protein that reversibly mediates the exchange of 1 Na[+] and 2 HCO[[3]][-] for 1 Cl[-] at basolateral membranes of gut and renal epithelia as well as CNS neurons. In the CNS, the product of Ndae1 can lower resting intracellular Cl[-] controlling GABA(A) Cl-channel activity. (1190 aa)    
Predicted Functional Partners:
CG13786
Uncharacterized protein.
      
 0.837
Tina-1
Troponin C-akin-1 protein; Putative gamma-glutamylcyclotransferase; Belongs to the gamma-glutamylcyclotransferase family.
      
 0.835
Prestin
FI18412p1; It is involved in the biological process described with: formate transport; sulfate transport; bicarbonate transport; oxalate transport; calcium ion transmembrane transport.
   
  
 0.732
Eglp2
Entomoglyceroporin 2, isoform C; Water channel activity; channel activity. It is involved in the biological process described with: transmembrane transport; renal system process; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.668
CG11836
Uncharacterized protein, isoform J; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
    
   0.667
ninaC
Neither inactivation nor afterpotential protein C; Required for photoreceptor cell function. The ninaC proteins combines putative serine/threonine-protein kinase and myosin activities. Essential for the expression and stability of the rtp protein in the photoreceptors. The rtp/ninaC complex is required for stability of inad and inac and the normal termination of phototransduction in the retina.
      
 0.662
Dnali1
Putative inner dynein arm light chain, axonemal; May play a dynamic role in flagellar motility.
   
  
 0.639
CG15429
AT30604p1; Belongs to the cytochrome b5 family.
   
  
 0.632
sxc
Super sex combs (sxc) is a polycomb group gene that encodes a O-GlcNAc transferase involved in epigenetic gene silencing.
   
    0.624
comt
Vesicle-fusing ATPase 1; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin; Belongs to the AAA ATPase family.
    
   0.604
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: medium (76%) [HD]