STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prelPreli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. (236 aa)    
Predicted Functional Partners:
CG30109
GEO09510p1.
   
 0.979
CG30108
Uncharacterized protein.
    
 
 0.933
retm
Protein real-time.
   
  
 0.915
slmo
Protein slowmo; Required to regulate peristaltic movement and also for germline proliferation in males and females.
  
0.844
ttm50
Mitochondrial import inner membrane translocase subunit TIM50-C; Tiny tim 50 (ttm50) encodes a mitochondrial inner membrane protein that is involved in mitochondrial protein translocation and maintenance of mitochondrial membrane potential. It plays active roles in regulating metabolic levels for modulation of growth in development.
   
  
 0.834
PPP1R15
Protein phosphatase 1 regulatory subunit 15 (PPP1R15) encodes a regulatory subunit of protein phosphatase 1. It mediates the dephosphorylation of the translation initiation factor encoded by eIF2alpha. This antagonises the effects of the stress sensing kinases encoded by PEK and Gcn2 promoting cap-dependent translation.
   
 
 0.716
Naa80
N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine. Preferentially acts on proteins starting with Asp- Asp-Asp and Glu-Glu-Glu sequences. In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu- Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp.
   
    0.641
Pisd
Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
   
 
 0.629
CLS
Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
   
 
 0.620
mRpS25
Probable 28S ribosomal protein S25, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
      
 0.603
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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