node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG30108 | Pisd | FBpp0271806 | FBpp0083921 | Uncharacterized protein. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | 0.424 |
CG30108 | prel | FBpp0271806 | FBpp0305218 | Uncharacterized protein. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.933 |
CG30108 | slmo | FBpp0271806 | FBpp0289088 | Uncharacterized protein. | Protein slowmo; Required to regulate peristaltic movement and also for germline proliferation in males and females. | 0.859 |
CG30109 | Pisd | FBpp0309237 | FBpp0083921 | GEO09510p1. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | 0.424 |
CG30109 | prel | FBpp0309237 | FBpp0305218 | GEO09510p1. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.979 |
CG30109 | slmo | FBpp0309237 | FBpp0289088 | GEO09510p1. | Protein slowmo; Required to regulate peristaltic movement and also for germline proliferation in males and females. | 0.955 |
CLS | Pisd | FBpp0084303 | FBpp0083921 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | 0.787 |
CLS | prel | FBpp0084303 | FBpp0305218 | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.620 |
Naa80 | prel | FBpp0100038 | FBpp0305218 | N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine. Preferentially acts on proteins starting with Asp- Asp-Asp and Glu-Glu-Glu sequences. In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu- Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.641 |
PPP1R15 | prel | FBpp0072113 | FBpp0305218 | Protein phosphatase 1 regulatory subunit 15 (PPP1R15) encodes a regulatory subunit of protein phosphatase 1. It mediates the dephosphorylation of the translation initiation factor encoded by eIF2alpha. This antagonises the effects of the stress sensing kinases encoded by PEK and Gcn2 promoting cap-dependent translation. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.716 |
PPP1R15 | ttm50 | FBpp0072113 | FBpp0312448 | Protein phosphatase 1 regulatory subunit 15 (PPP1R15) encodes a regulatory subunit of protein phosphatase 1. It mediates the dephosphorylation of the translation initiation factor encoded by eIF2alpha. This antagonises the effects of the stress sensing kinases encoded by PEK and Gcn2 promoting cap-dependent translation. | Mitochondrial import inner membrane translocase subunit TIM50-C; Tiny tim 50 (ttm50) encodes a mitochondrial inner membrane protein that is involved in mitochondrial protein translocation and maintenance of mitochondrial membrane potential. It plays active roles in regulating metabolic levels for modulation of growth in development. | 0.726 |
Pisd | CG30108 | FBpp0083921 | FBpp0271806 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | Uncharacterized protein. | 0.424 |
Pisd | CG30109 | FBpp0083921 | FBpp0309237 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | GEO09510p1. | 0.424 |
Pisd | CLS | FBpp0083921 | FBpp0084303 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | 0.787 |
Pisd | prel | FBpp0083921 | FBpp0305218 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.629 |
mRpS25 | prel | FBpp0073762 | FBpp0305218 | Probable 28S ribosomal protein S25, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation. | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | 0.603 |
prel | CG30108 | FBpp0305218 | FBpp0271806 | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | Uncharacterized protein. | 0.933 |
prel | CG30109 | FBpp0305218 | FBpp0309237 | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | GEO09510p1. | 0.979 |
prel | CLS | FBpp0305218 | FBpp0084303 | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. | 0.620 |
prel | Naa80 | FBpp0305218 | FBpp0100038 | Preli-like (prel) encodes a mitochondrial protein in the PRELI/MSF1 family that contributes to the integrity of mitochondrial structures and the activity of respiratory chain complex IV. | N-alpha-acetyltransferase 80; N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine. Preferentially acts on proteins starting with Asp- Asp-Asp and Glu-Glu-Glu sequences. In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu- Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp. | 0.641 |