node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG11679 | Gss2 | FBpp0073982 | FBpp0290197 | GM02445p; It is involved in the biological process described with: positive regulation of mitochondrial translation. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.588 |
CG4752 | Gart | FBpp0071743 | FBpp0308722 | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.685 |
CG4752 | Gclc | FBpp0071743 | FBpp0309124 | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | 0.904 |
CG4752 | Gclm | FBpp0071743 | FBpp0306672 | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | 0.901 |
CG4752 | Gss2 | FBpp0071743 | FBpp0290197 | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.418 |
Drice | Gss2 | FBpp0084848 | FBpp0290197 | Caspase subunit p12; Death related ICE-like caspase (Drice) encodes a major effector apoptotic caspase. It is essential for both developmental and damaged induced cell death, as well as several non-apoptotic vital cellular processes. It is activated by the product of Dark and the initiator caspase encoded by Dronc and is inhibited by the inhibitor of apoptosis encoded by Diap1; Belongs to the peptidase C14A family. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.533 |
Gart | CG4752 | FBpp0308722 | FBpp0071743 | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | 0.685 |
Gart | Gss2 | FBpp0308722 | FBpp0290197 | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.526 |
Gart | P5CS | FBpp0308722 | FBpp0301603 | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.801 |
Gclc | CG4752 | FBpp0309124 | FBpp0071743 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | 0.904 |
Gclc | Gclm | FBpp0309124 | FBpp0306672 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | 0.999 |
Gclc | Gss2 | FBpp0309124 | FBpp0290197 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.562 |
Gclc | P5CS | FBpp0309124 | FBpp0301603 | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.649 |
Gclm | CG4752 | FBpp0306672 | FBpp0071743 | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | 0.901 |
Gclm | Gclc | FBpp0306672 | FBpp0309124 | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | Glutamate-cysteine ligase catalytic subunit (Gclc) encodes a heterodimeric enzyme involved in the first rate-limiting step of glutathione synthesis. It binds L-cysteine and L-glutamate to form gamma-glutamylcysteine; Belongs to the glutamate--cysteine ligase type 3 family. | 0.999 |
Gclm | Gss2 | FBpp0306672 | FBpp0290197 | Glutamate-cysteine ligase modifier subunit (Gclm) encodes a protein that regulates the ligase activity of the product of Gclc. It is involved in glutathione biosynthesis, arsenic detoxification and response to ethanol. | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | 0.495 |
Gss2 | CG11679 | FBpp0290197 | FBpp0073982 | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | GM02445p; It is involved in the biological process described with: positive regulation of mitochondrial translation. | 0.588 |
Gss2 | CG4752 | FBpp0290197 | FBpp0071743 | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | FI03324p; 5-oxoprolinase (ATP-hydrolyzing) activity. It is involved in the biological process described with: glutathione metabolic process. | 0.418 |
Gss2 | Drice | FBpp0290197 | FBpp0084848 | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | Caspase subunit p12; Death related ICE-like caspase (Drice) encodes a major effector apoptotic caspase. It is essential for both developmental and damaged induced cell death, as well as several non-apoptotic vital cellular processes. It is activated by the product of Dark and the initiator caspase encoded by Dronc and is inhibited by the inhibitor of apoptosis encoded by Diap1; Belongs to the peptidase C14A family. | 0.533 |
Gss2 | Gart | FBpp0290197 | FBpp0308722 | ATP binding; glutathione synthase activity. It is involved in the biological process described with: glutathione biosynthetic process; detoxification of arsenic-containing substance. | Trifunctional purine biosynthetic protein adenosine-3; GART trifunctional enzyme (Gart) encodes a multifunctional enzyme that exhibits phosphoribosylamine-glycine ligase, phosphoribosylformylglycinamidine cyclo-ligase and phosphoribosylglycinamide formyltransferase activities; In the N-terminal section; belongs to the GARS family. In the C-terminal section; belongs to the GART family. | 0.526 |