node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apf | CG32305 | FBpp0079490 | FBpp0290537 | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | 0.901 |
Apf | CG8891 | FBpp0079490 | FBpp0078684 | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.933 |
Apf | Mocs1 | FBpp0079490 | FBpp0075935 | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | Cyclic pyranopterin monophosphate synthase; Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). Mocs1a catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and Mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | 0.815 |
Apf | Pu | FBpp0079490 | FBpp0071507 | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | GTP cyclohydrolase 1; Isoform B is required for eye pigment production, Isoform C may be required for normal embryonic development and segment pattern formation. | 0.808 |
CG10581 | CG31793 | FBpp0077982 | FBpp0080682 | IP06402p; Nucleotide phosphatase activity, acting on free nucleotides. | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | 0.900 |
CG10581 | CG32305 | FBpp0077982 | FBpp0290537 | IP06402p; Nucleotide phosphatase activity, acting on free nucleotides. | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | 0.901 |
CG31793 | CG10581 | FBpp0080682 | FBpp0077982 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | IP06402p; Nucleotide phosphatase activity, acting on free nucleotides. | 0.900 |
CG31793 | CG32305 | FBpp0080682 | FBpp0290537 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | 0.900 |
CG32305 | Apf | FBpp0290537 | FBpp0079490 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | 0.901 |
CG32305 | CG10581 | FBpp0290537 | FBpp0077982 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | IP06402p; Nucleotide phosphatase activity, acting on free nucleotides. | 0.901 |
CG32305 | CG31793 | FBpp0290537 | FBpp0080682 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | 0.900 |
CG32305 | CG8891 | FBpp0290537 | FBpp0078684 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
CG32305 | Mocs1 | FBpp0290537 | FBpp0075935 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | Cyclic pyranopterin monophosphate synthase; Isoform Mocs1a and isoform Mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). Mocs1a catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and Mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the C-terminal section; belongs to the MoaC family. | 0.804 |
CG32305 | Pka-C1 | FBpp0290537 | FBpp0089382 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | cAMP-dependent protein kinase catalytic subunit 1; Serine/threonine-protein kinase involved in memory formation. Promotes long-term memory by phosphorylating meng and by regulating CrebB protein stability and activity. As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology when anchored to the membrane. | 0.904 |
CG32305 | Pka-C2 | FBpp0290537 | FBpp0085089 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | ATP binding; protein serine/threonine kinase activity; cAMP-dependent protein kinase activity; protein kinase A regulatory subunit binding. It is involved in the biological process described with: protein kinase A signaling; peptidyl-serine phosphorylation. | 0.904 |
CG32305 | Pu | FBpp0290537 | FBpp0071507 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | GTP cyclohydrolase 1; Isoform B is required for eye pigment production, Isoform C may be required for normal embryonic development and segment pattern formation. | 0.800 |
CG32305 | Ras85D | FBpp0290537 | FBpp0081600 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | Ras-like protein 1; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells. During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis. | 0.942 |
CG32305 | dnc | FBpp0290537 | FBpp0305507 | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | Dunce (dnc) encodes a cAMP-specific phosphodiesterase, responsible for cAMP degradation. dnc product plays a pivotal role in neurological and behavioral plasticity including synaptic development and function, learning and courtship. The product of dnc is also known to affect regulation of several developmental processes such as oogenesis; Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. | 0.816 |
CG8891 | Apf | FBpp0078684 | FBpp0079490 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Diadenosine tetraphosphate hydrolase; Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity. | 0.933 |
CG8891 | CG32305 | FBpp0078684 | FBpp0290537 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein; Adenylate cyclase activity. It is involved in the biological process described with: cyclic nucleotide biosynthetic process; adenylate cyclase-activating G protein-coupled receptor signaling pathway. | 0.900 |