STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
Task6TWIK-related acid-sensitive K[+] channel 6 (Task6) encodes an ion channel involved in the transmembrane transport of potassium. (408 aa)    
Predicted Functional Partners:
CG42594
Uncharacterized protein, isoform C; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.894
Task7
TWIK-related acid-sensitive K[+] channel 7 (Task7) encodes an ion channel involved in the transmembrane transport of potassium.
  
  
0.815
CG10864
Uncharacterized protein; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.793
CG1688
BcDNA.GH04802; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: stabilization of membrane potential; potassium ion transmembrane transport; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.724
Irk2
Inwardly rectifying potassium channel 2 (Irk2) encodes a protein that is required in transepithelial fluid secretion and potassium transport in the Malpighian tubule. It contributes to wing patterning, through the regulation of release of the product of dpp.
   
  
 0.687
Rgk2
Rad, Gem/Kir family member 2 (Rgk2) encodes a protein that regulates voltage-gated calcium channel activity.
   
    0.687
CG4928
UNC93-like protein; Potassium channel regulator activity. It is involved in the biological process described with: regulation of muscle contraction; regulation of potassium ion transport.
      
 0.686
galene
FI03418p; Potassium channel activity; potassium ion leak channel activity. It is involved in the biological process described with: potassium ion transmembrane transport; stabilization of membrane potential; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.682
Ork1
Open rectifier K[+] channel 1 (Ork1) encodes a member of the two pore open rectifier potassium channel gene family. It contributes to the regulation of membrane resting potential. The primary gating mechanism for the product of Ork1 appears to be based on phosphorylation of multiple serine, threonine and tyrosine residues in the large intracellular C-terminal tail.
     
0.672
sand
RE21922p; Potassium ion leak channel activity; potassium channel activity. It is involved in the biological process described with: negative regulation of membrane potential; negative regulation of circadian sleep/wake cycle, sleep; stabilization of membrane potential; potassium ion transmembrane transport; cellular response to dopamine; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.655
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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