STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ReepBReceptor expression-enhancing protein; It is involved in the biological process described with: regulation of intracellular transport; endoplasmic reticulum tubular network organization; endoplasmic reticulum organization. (178 aa)    
Predicted Functional Partners:
Rtnl1
Reticulon-like1 (Rtnl1) encodes a reticulon family member, with predicted intramembrane hairpin domains that can insert into the cytosolic face of the endoplasmic reticulum (ER), thereby curving it and promoting ER tubule formation. It is enriched on tubular ER, including axons and egg chamber fusomes.
   
 
 0.848
Sec61beta
Sec61 beta subunit (Sec61beta) encodes a protein involved in the regulation of autophagy.
   
 
 0.819
Yip1d1
Protein YIPF; It is involved in the biological process described with: positive regulation of synapse pruning; spermatogenesis.
   
 
 0.771
Tapdelta
Translocon-associated protein delta, isoform A.
   
    0.741
bai
Transmembrane emp24 domain-containing protein bai; Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected; Belongs to the EMP24/GP25L family.
   
    0.721
sturkopf
Lipid droplet-associated hydrolase; Sturkopf (sturkopf) encodes an evolutionary conserved lipid droplet-associated protein. In the absence of lipid droplets, the protein localizes to the endoplasmic reticulum; Belongs to the AB hydrolase superfamily. LDAH family.
   
  
 0.697
CG17734
Uncharacterized protein, isoform C; It is involved in the biological process described with: mitochondrial respirasome assembly; behavioral response to ethanol.
   
  
 0.682
Arl6IP1
ARL-6-interacting protein 1 homolog; It is involved in the biological process described with: endoplasmic reticulum tubular network membrane organization.
    
 
 0.679
Tsp5D
Tetraspanin.
    
 
 0.673
CG11825
Uncharacterized protein, isoform C; It is involved in the biological process described with: mitochondrial respirasome assembly; copper ion homeostasis.
      
 0.608
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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