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DCP2 protein (fruit fly) - STRING interaction network
"DCP2" - Decapping protein 2, isoform E in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
DCP2Decapping protein 2, isoform E; Protein binding; RNA binding; manganese ion binding; m7G(5’)pppN diphosphatase activity. It is involved in the biological process described with- nuclear-transcribed mRNA catabolic process; regulation of cytoplasmic mRNA processing body assembly; deadenylation-dependent decapping of nuclear-transcribed mRNA; gene silencing by miRNA (792 aa)    
Predicted Functional Partners:
DCP1
Decapping protein 1, isoform A; Protein binding. It is involved in the biological process described with- nuclear-transcribed mRNA catabolic process; regulation of cytoplasmic mRNA processing body assembly; pole plasm oskar mRNA localization; gene silencing by miRNA; positive regulation of gene silencing by miRNA (372 aa)
     
  0.999
Edc3
Enhancer of mRNA-decapping protein 3; In the process of mRNA degradation, may play a role in mRNA decapping (680 aa)
   
  0.999
Ge-1
Enhancer of mRNA-decapping protein 4 homolog; In the process of mRNA degradation, seems to play a role in mRNA decapping. Required for silencing a subset of endogenous miRNA targets (1354 aa)
     
  0.998
pcm
5’-3’ exoribonuclease activity; nucleic acid binding (1613 aa)
     
  0.996
me31B
Putative ATP-dependent RNA helicase me31b; Unwinds RNA in an ATP-dependent fashion (Potential). Involved in germ cell formation (459 aa)
   
  0.994
LSm1
IP04848p; It is involved in the biological process described with- RNA processing; mRNA splicing, via spliceosome; cytoplasmic mRNA processing body assembly (137 aa)
       
  0.993
CG17768
Uncharacterized protein, isoform A; U6 snRNA binding (154 aa)
     
  0.991
CG10418
U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3’-terminal U-tract of U6 snRNA (95 aa)
     
  0.990
LSm7
Like Sm 7, isoform A; It is involved in the biological process described with- mRNA splicing, via spliceosome; neurogenesis (110 aa)
     
  0.987
Patr-1
Protein associated with topo II related-1, isoform A; It is involved in the biological process described with- deadenylation-dependent decapping of nuclear-transcribed mRNA; negative regulation of synaptic growth at neuromuscular junction; cytoplasmic mRNA processing body assembly (968 aa)
     
 
  0.981
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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