Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BicC | Imp | FBpp0080361 | FBpp0293680 | Protein bicaudal C; RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression. | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.623 |
| BicC | mub | FBpp0080361 | FBpp0293521 | Protein bicaudal C; RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression. | Mushroom-body expressed, isoform K; Mushroom-body expressed (mub) encodes a protein involved in thermosensory behavior and regulation of alternative mRNA splicing. | 0.691 |
| BicC | sqd | FBpp0080361 | FBpp0082320 | Protein bicaudal C; RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression. | RNA-binding protein squid; This protein is a component of ribonucleosomes. Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle. At least one of the isoforms is essential in somatic tissues. | 0.468 |
| BicC | yps | FBpp0080361 | FBpp0075759 | Protein bicaudal C; RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression. | Ypsilon schachtel, isoform A; Nucleic acid binding; protein binding; mRNA binding. It is involved in the biological process described with: oogenesis; mRNA splicing, via spliceosome; regulation of gene expression. | 0.440 |
| Imp | BicC | FBpp0293680 | FBpp0080361 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Protein bicaudal C; RNA-binding protein that is involved in oogenesis. Required for correct targeting of the migrating anterior follicle cells and the establishment of anterior-posterior polarity in the oocyte. May act as translational repressor of oskar during oogenesis. Function seems to be sensitive to small changes in expression. | 0.623 |
| Imp | ImpL2 | FBpp0293680 | FBpp0073106 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Neural/ectodermal development factor IMP-L2; Essential developmental role during embryogenesis, in particular the normal development of the nervous system. May be involved in some aspect of cell adhesion. | 0.557 |
| Imp | Mettl14 | FBpp0293680 | FBpp0079219 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | N6-adenosine-methyltransferase non-catalytic subunit; Non-catalytic component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. In the heterodimer formed with Ime4/Mettl3, Mettl14 constitutes the RNA- binding scaffold that recognizes the substrate rather than the catalytic core (By similarity). Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and pro [...] | 0.594 |
| Imp | Mkrn1 | FBpp0293680 | FBpp0078038 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | 0.584 |
| Imp | Syp | FBpp0293680 | FBpp0306764 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Syncrip, isoform J; Syncrip (Syp) encodes an RNA-binding protein that regulates the localization and translation of mRNAs involved in multiple processes. It is required for synapse morphology and synaptic transmission at the neuromuscular junction as well as being involved in oocyte axis specification and control of neuronal cell fates in the mushroom body. | 0.674 |
| Imp | Ythdc1 | FBpp0293680 | FBpp0072940 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. Acts by acting as a reader of m6A methylation. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. | 0.658 |
| Imp | lin-28 | FBpp0293680 | FBpp0076798 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Protein lin-28 homolog; mRNA binding; zinc ion binding; mRNA 3'-UTR binding; Belongs to the lin-28 family. | 0.665 |
| Imp | mub | FBpp0293680 | FBpp0293521 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Mushroom-body expressed, isoform K; Mushroom-body expressed (mub) encodes a protein involved in thermosensory behavior and regulation of alternative mRNA splicing. | 0.544 |
| Imp | sqd | FBpp0293680 | FBpp0082320 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | RNA-binding protein squid; This protein is a component of ribonucleosomes. Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle. At least one of the isoforms is essential in somatic tissues. | 0.729 |
| Imp | yps | FBpp0293680 | FBpp0075759 | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | Ypsilon schachtel, isoform A; Nucleic acid binding; protein binding; mRNA binding. It is involved in the biological process described with: oogenesis; mRNA splicing, via spliceosome; regulation of gene expression. | 0.543 |
| ImpL2 | Imp | FBpp0073106 | FBpp0293680 | Neural/ectodermal development factor IMP-L2; Essential developmental role during embryogenesis, in particular the normal development of the nervous system. May be involved in some aspect of cell adhesion. | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.557 |
| Mettl14 | Imp | FBpp0079219 | FBpp0293680 | N6-adenosine-methyltransferase non-catalytic subunit; Non-catalytic component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. In the heterodimer formed with Ime4/Mettl3, Mettl14 constitutes the RNA- binding scaffold that recognizes the substrate rather than the catalytic core (By similarity). Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and pro [...] | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.594 |
| Mettl14 | Ythdc1 | FBpp0079219 | FBpp0072940 | N6-adenosine-methyltransferase non-catalytic subunit; Non-catalytic component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination. In the heterodimer formed with Ime4/Mettl3, Mettl14 constitutes the RNA- binding scaffold that recognizes the substrate rather than the catalytic core (By similarity). Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and pro [...] | YTH domain-containing protein 1; Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. Acts by acting as a reader of m6A methylation. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy. M6A methylation is also required for neuronal functions. | 0.991 |
| Mkrn1 | Imp | FBpp0078038 | FBpp0293680 | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.584 |
| Mkrn1 | sqd | FBpp0078038 | FBpp0082320 | Makorin 1, isoform A; Ubiquitin protein ligase activity; metal ion binding; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination; positive regulation of insulin receptor signaling pathway; positive regulation of oogenesis. | RNA-binding protein squid; This protein is a component of ribonucleosomes. Could be needed to organize a concentration gradient of a dorsalizing morphogen (Dm) originating in the germinal vesicle. At least one of the isoforms is essential in somatic tissues. | 0.471 |
| Syp | Imp | FBpp0306764 | FBpp0293680 | Syncrip, isoform J; Syncrip (Syp) encodes an RNA-binding protein that regulates the localization and translation of mRNAs involved in multiple processes. It is required for synapse morphology and synaptic transmission at the neuromuscular junction as well as being involved in oocyte axis specification and control of neuronal cell fates in the mushroom body. | IGF-II mRNA-binding protein (Imp) encodes a protein that regulates the stability, translation and/or transport of its associated mRNAs, a large number of them encoding F-actin regulators. It is an essential protein required for neural and germline stem cell maturation, neuronal remodeling, as well as the expression modulation of asymmetrically localized maternal mRNAs. | 0.674 |
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